Transporters as Targets for Drugs

Herausgegeben:Napier, Susan; Bingham, Matilda

• Broschiertes Buch

Produktbeschreibung

M. Bingham - S. Napier: Overview: Transporters as Targets for Drug Discovery

I. Sylte - A.W. Ravna - G. Sager - S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design

G.A. Whitlock - M.D. Andrews - A.D. Brown - P.V Fish - A. Stobie - F. Wakehut: Design of Monoamine Reuptake Inhibitors - SSRIs, SNRIs and NRIs

A. Hauck Newman - J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter

Z. Chen - J. Yang - P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors

G. Antoni - J. Sörensen - H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography

R. Bridges - S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc

R. Gilfillan - J. Kerr G. - Walker - G. Wishart: Glycine Transporters and Their Inhibitors

Produktdetails

• Topics in Medicinal Chemistry 4
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-642-09969-4
• Softcover reprint of hardcover 1st ed. 2009
• Seitenzahl: 268
• Erscheinungstermin: 28. Oktober 2010
• Englisch
• Abmessung: 235mm x 155mm x 17mm
• Gewicht: 407g
• ISBN-13: 9783642099694
• ISBN-10: 3642099696
• Artikelnr.: 33707459

Inhaltsangabe

Overview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter.- The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.