TRP Channels

Herausgeber: Zhu, Michael X

• Broschiertes Buch

Produktbeschreibung

Providing detailed methods for the study of transient receptor potential (TRP) channels and their role in a wide variety of cellular functions, this book includes expression and functional studies of TRP channels in heterologous systems as well as structural and functional studies of TRP channels. The author also explores various methods for detailed analysis of biophysical properties of TRP channels. In addition, the text covers high-throughput screening assays for TRP channels and offers novel and effective approaches to study endogenous TRP channel function in native systems.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 500
• Erscheinungstermin: 12. September 2017
• Englisch
• Abmessung: 234mm x 156mm x 26mm
• Gewicht: 694g
• ISBN-13: 9781138116160
• ISBN-10: 1138116165
• Artikelnr.: 57049975

Autorenporträt

Michael Xi Zhu is currently with the Department of Integrative Biology and Pharmacology at the University of Texas Health Science Center at Houston

Inhaltsangabe

High-Throughput Screening of TRPC Channel Ligands Using Cell-Based Assays.
Methods to Study TRPC Channel Regulation by Interacting Proteins.
Activation of TRP Channels in Mammalian Systems. Studying Subunit
Interaction and Complex Assembly of TRP Channels. Proteomic Analysis of
TRPC Channels. Lessons of Studying TRP Channels with Antibodies. Assessing
TRPC Channel Function Using Pore-Blocking Antibodies. Strategies and
Protocols to Generate Mouse Models with Targeted Mutations to Analyze TRP
Channel Functions. Studying Endogenous TRP Channels in Visceral and
Vascular Smooth Muscles. TRPC Channels in Neuronal Survival.
Electrophysiological Methods for the Study of TRP Channels. High-Throughput
Approaches to Study Mechanisms of TRP Channel Activation. Methods Used for
Studying TRP Channel Functions in Sensory Neurons. Time-Resolved Activation
of Thermal TRP Channels by Fast Temperature Jumps Fluorescence Microscopy
in Thermo TRP Channel Research. Regulation of TRP Channels by
Osmomechanical Stress. Study of TRP Channels in Cancer Cells. In Vitro and
In Vivo Assays for the Discovery of Analgesic Drugs Targeting TRP Channels.
Studying TRP Channels in Intracellular Membranes. Methods for Studying
Drosophila TRP Channels. Studying TRP Channels in Caenorhabditis elegans.
Index.