Roshna Sankar NS, Saloni Verma, Shalini Gupta

Tumor Microenvironment

Deciphering Tumor Microenvironment for Predicting Outcomes in Head and Neck Cancer

• Broschiertes Buch

Produktbeschreibung

The document systematically explores the tumor microenvironment (TME) within the context of head and neck squamous cell carcinoma (HNSCC), elucidating its multifaceted nature and profound influence on cancer progression and treatment outcomes. Firstly, it delineates the various components constituting the TME, ranging from cellular elements such as cancer-associated fibroblasts, vascular endothelial cells, immune cells (macrophages, neutrophils, lymphocytes, mast cells, natural killer cells), and platelets, to the extracellular matrix and cancer stem cells. This comprehensive overview underscores the complexity of the TME and highlights the diverse interactions among its constituents. Furthermore, the document delves into the role of the TME at different stages of HNSCC pathogenesis, elucidating its involvement in premalignant lesion development and primary tumor progression. It also examines the molecular crosstalk between genetic and epigenetic alterations and their impact on shaping the TME in HNSCC, providing insights into the underlying mechanisms driving cancer aggressiveness.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 88
• Erscheinungstermin: 28. März 2024
• Englisch
• Abmessung: 220mm x 150mm x 6mm
• Gewicht: 149g
• ISBN-13: 9786207476527
• ISBN-10: 6207476522
• Artikelnr.: 70425200

Autorenporträt

Hi, I'm Roshna, an aspiring dentist currently specializing in Oral Pathology and Microbiology at KGMU, Lucknow. Through my MDS journey, I'm dedicated to understanding oral diseases better and improving patient care. I'm particularly passionate about research, exploring the molecular intricacies of oral pathology and microbiology.