This work is part of a final year project carried out and defended at the Central University of Paramedical Sciences in Tunisia.It explores the professional and psychological characteristics of the Tunisian nurse in the prison environment.We found that nurses working in the prison environment can face a variety of professional and psychological difficulties due to the particular nature of their working environment.The most marked difficulties were related to the problem of security as well as violence and trauma. These professionals may witness physical or verbal violence between inmates, or even be victims of aggression themselves. These experiences can be costly and psychologically traumatic. Add to this overcrowding and lack of resources, the mental health of inmates, etc. These difficulties had a significant impact on the well-being of nurses working in prisons, and it was essential to put in place support measures, such as stress management training programs and psychological support services.