Twin and Family Studies of Epigenetics

Volume 27
Herausgeber: Li, Shuai; O Tollefsbol, Trygve; Hopper, John

• Broschiertes Buch

Produktbeschreibung

Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects.

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Produktdetails

• Verlag: Elsevier Science
• Seitenzahl: 374
• Erscheinungstermin: 20. August 2021
• Englisch
• Gewicht: 750g
• ISBN-13: 9780128209516
• ISBN-10: 0128209518
• Artikelnr.: 62272844

Inhaltsangabe

ART 1 Introduction 1. Value of twin and family study designs for epigenetic
research 2. Evaluation and measurement of epigenetic modifications in
population-based studies
PART 2 Human health applications 3. Discordant monozygotic twin studies of
epigenetic mechanisms in mental health 4. DNA methylation and breast cancer
risk: value of twin and family studies 5. Twin and family studies on
epigenetics and oral health 6. Twin and family epigenetic studies of type 2
diabetes 7. Twin and family studies on epigenetics and obesity 8. DNA
methylation and blood pressure in Chinese adult twins 9. Twin and family
studies on epigenetics of autoimmune diseases 10. Twin studies on the
epigenetics of selected neurological disorders and carotid artery disease
11. Disease-discordant twin studies of epigenetics and cancer 12. Sex
differences in epigenetic profiles: The value of twin studies
PART 3 Emerging approach 13. Combining twin-family designs with measured
genetic variants to study the causes of epigenetic variation 14. Imaging
epigenetics and the radiogenomics 15. DNA methylation changes specific to
environmental exposures: The strengths of twin studies using cigarette
smoking as an example 16. Time trends in epigenetic signatures and
population health risks 17. Ambient air pollution and human epigenetic
modifications