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Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host…mehr

Produktbeschreibung
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.
Autorenporträt
Prof. Dr. rer. nat. Steffen Backert Chair of Microbiology Friedrich Alexander University Erlangen/Nuremberg Department of Biology Division of Microbiology Staudtstr. 5 D-91058 Erlangen Germany Tel.  ++49 9131 8528081 Fax  ++49 9131 8528082  Prof. Dr. techn. Elisabeth Grohmann Professor of Microbiology Beuth University of Applied Sciences Berlin Department of Life Sciences and Technology Division of Microbiology Forum Seestraße Seestr. 64 D-13347 Berlin Germany Tel. ++49 30 45043942 Fax ++49 30 45043983