High Quality Content by WIKIPEDIA articles! In the U.S. state of California, U.S. Route 50 (US 50) runs east from I-80 in West Sacramento to the Nevada state line in South Lake Tahoe. The western half of the highway, from I-80 through Sacramento and Placerville to the canyon of the South Fork American River at Riverton, is a four-or-more-lane divided highway, mostly built to freeway standards. The remainder, passing through the canyon, over the Sierra Nevada at Echo Summit, and into the Lake Tahoe Basin, is a mainly two-lane road, although it has been added to the California Freeway and Expressway System by the state legislature.