Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In enzymology, an UDP-glucuronate 5''-epimerase (EC 5.1.3.12) is an enzyme that catalyzes the chemical reaction. UDP-glucuronate = UDP-L-iduronate. Hence, this enzyme has one substrate, UDP-glucuronate, and one product, UDP-L-iduronate. This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is UDP-glucuronate 5''-epimerase. Other names in common use include uridine diphosphoglucuronate 5''-epimerase, UDP-glucuronic acid 5''-epimerase, and C-5-uronosyl epimerase. This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, NAD+.