The text brings together the evidence for the fundamental significance of ultradian rhythms at all levels of organization. In lower eukaryotes short-period rhythms (30-70 min.) are coupled to an ultradian clock which serves as a central time-keeper. In metazoans, similar rhythms are necessary for inter-cell communication, and temporal coupling for the coordination of integrated functions of tissues and organs in order to provide the "homodynamics" of the whole organism. Electrical, endocrine, and behavioral rhythms characterize both wakefulness and sleep, and pathologically disordered states…mehr
The text brings together the evidence for the fundamental significance of ultradian rhythms at all levels of organization. In lower eukaryotes short-period rhythms (30-70 min.) are coupled to an ultradian clock which serves as a central time-keeper. In metazoans, similar rhythms are necessary for inter-cell communication, and temporal coupling for the coordination of integrated functions of tissues and organs in order to provide the "homodynamics" of the whole organism. Electrical, endocrine, and behavioral rhythms characterize both wakefulness and sleep, and pathologically disordered states give rise to dynamic diseases. We can now trace a continuum from the molecular genetic, through the cellular and neuroendocrine, to the behavioral and psychosocial levels. Specialist chapters devoted to each of these topics (each with a general introductory section and some speculative discussions) are provided.
From the contents: Part I: The Molecular-Genetic-Cellular Level: Intracellular timekeeping.- Rhythms of protein synthesis and other circahoralian oscillations.- Oscillations and cancer.- Genetic and molecular analysis of ultradian rhythms in Drosophila.- Part II: The Neuroendocrinal and Developmental Level: Endocrine ultradian rhythms during sleep and wakefulness.- Phase plots of temporal oscillations.- Ontogenesis of ultradian biological rhythms.- Ultradian rhythms of metabolism, endocrinology and behaviour.- Part III: The Behavioral and Psychosocial Level: Ultradian behaviour cycles in humans.- The basic rest-activity cycle, 32 years later: An interview with Nathanial Kleitman at 96.- Reality, stress, and imagination in temporal isolation experiments: An interview with Rütger Wever.- Human biological rhythms - the unification hypothesis of chronobiology and psychobiology.
From the contents: Part I: The Molecular-Genetic-Cellular Level: Intracellular timekeeping.- Rhythms of protein synthesis and other circahoralian oscillations.- Oscillations and cancer.- Genetic and molecular analysis of ultradian rhythms in Drosophila.- Part II: The Neuroendocrinal and Developmental Level: Endocrine ultradian rhythms during sleep and wakefulness.- Phase plots of temporal oscillations.- Ontogenesis of ultradian biological rhythms.- Ultradian rhythms of metabolism, endocrinology and behaviour.- Part III: The Behavioral and Psychosocial Level: Ultradian behaviour cycles in humans.- The basic rest-activity cycle, 32 years later: An interview with Nathanial Kleitman at 96.- Reality, stress, and imagination in temporal isolation experiments: An interview with Rütger Wever.- Human biological rhythms - the unification hypothesis of chronobiology and psychobiology.
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