A neurologist whose father suffers from Parkinson's provides a layreader-friendly explanation of the disease, its history, development, treatment and modern advances that may ultimately lead to a cure. Rosenbaum's professional view is as a clinical neurologist who regularly cares for patients with the progressive neurological deterioration caused by Parkinson's Disease. His personal experience with his father, a retired surgeon, further powers his quest to give patients, family members and caregivers what they need to know. Topics covered include challenges of correct diagnosis, variations in…mehr
A neurologist whose father suffers from Parkinson's provides a layreader-friendly explanation of the disease, its history, development, treatment and modern advances that may ultimately lead to a cure. Rosenbaum's professional view is as a clinical neurologist who regularly cares for patients with the progressive neurological deterioration caused by Parkinson's Disease. His personal experience with his father, a retired surgeon, further powers his quest to give patients, family members and caregivers what they need to know. Topics covered include challenges of correct diagnosis, variations in prognosis, investigations of causes including exciting progress in possible toxins and genetic factors that play a role, and different treatment options including natural remedies as well as new drugs for symptom treatment. Rosenbaum also explains research efforts to find a preventative drug, modern surgical options and hopes for stem cell or gene therapy. In this work, Rosenbaum blends historical and medical research with illustrations from the patients in his professional life, and from his dad on the homefront, to give us a clear and comprehensive understanding of Parkinson's. He also includes writing from and attention to well-known individuals affected by this disorder-among them actor Michael J. Fox.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
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Autorenporträt
Richard B. Rosenbaum M.D.
Inhaltsangabe
Acknowledgments Introduction 1. THE DIAGNOSTIC CONVERSATION-DIAGNOSIS AND PROGNOSIS OF PARKINSON'S DISEASE Making the Diagnosis James Parkinson and the Shaking Palsy Jean Charcot and Better Examinations Checking Diagnostic Accuracy Specificity and Sensitivity Prognosis The Hoehn and Yahr Scale The Unified Parkinson's Disease Rating Scale 2. PATHOLOGY OF PARKINSON'S DISEASE What Part of the Brain Fails in Parkinson's Disease? Nerve Cell Connections Chemical Pathology of Parkinson's Disease 3. IS THERE AN EPIDEMIC OF PARKINSON'S DISEASE? Epidemiology of Parkinson's Disease John Snow-The Father of Epidemiology Koch's Postulates Investigating Clusters of Parkinson's Disease Kuru and Creutzfeldt-Jakob Disease Does Smoking Cause Parkinson's Disease? Causation versus Association-The Hill Criteria Epidemiology of Smoking and Parkinson's Disease Pesticides, Head Trauma, and Parkinson's Disease Parkinson's at the Manor 4. CAUSES OF PARKINSON'S DISEASE Does an Infection Cause Parkinson's Disease? When Prophecy Fails Do Toxins Cause Parkinson's Disease? An Answer from the Frozen Addicts Do Genes Cause Parkinson's Disease? All Disease Is Genetic Disease 5. MEDICATIONS FOR PARKINSON'S DISEASE The Herbal Tradition Herbal Treatment of Parkinson's Disease Awakenings-L-Dopa Therapy Dopamine and Schizophrenia-The Dopamine Receptor Rational Drug Therapy-Trying to Prevent Progression of Parkinson's Disease Coenzyme Q10-Another Quest for Neuroprotection The Challenges of Taking L-Dopa 6. IMAGES OF THE BRAIN-A PICTURE OF THE BRAIN IS WORTH A THOUSAND WORDS Imaging and Diagnosis Imaging and Presymptomatic Diagnosis Imaging and Disease Progression 7. A BETTER MODEL OF PARKINSON'S DISEASE Dopamine Nerve Cells Connect to Many Parts of the Brain Dopamine is One of Many Neurotransmitters That Are Important in Parkinson's Disease Patients with Parkinson's Disease Lose Cells from Many Areas of the Brain 8. BRAIN SURGERY FOR PARKINSON'S DISEASE Can Destroying Part of the Brain Be Good? "Brain Transplantation"-Implanting New Brain Cells Gene Therapy 9. LIVING WITH PARKINSON'S DISEASE Mood, Behavior, and Parkinson's Disease Can L-Dopa Make People Gamble? Are Parkinson's Disease and Alzheimer's Disease Related? Sleep and Parkinson's Disease Fall and Injury Prevention 10. CONCLUSIONS What Happens to Brain Cells to Cause Parkinson's Disease? Living Better with Parkinson's Disease The Story of Parkinson's Disease Is Not Finished Appendix: Reading about Parkinson's Disease Glossary Notes Index
Acknowledgments Introduction 1. THE DIAGNOSTIC CONVERSATION-DIAGNOSIS AND PROGNOSIS OF PARKINSON'S DISEASE Making the Diagnosis James Parkinson and the Shaking Palsy Jean Charcot and Better Examinations Checking Diagnostic Accuracy Specificity and Sensitivity Prognosis The Hoehn and Yahr Scale The Unified Parkinson's Disease Rating Scale 2. PATHOLOGY OF PARKINSON'S DISEASE What Part of the Brain Fails in Parkinson's Disease? Nerve Cell Connections Chemical Pathology of Parkinson's Disease 3. IS THERE AN EPIDEMIC OF PARKINSON'S DISEASE? Epidemiology of Parkinson's Disease John Snow-The Father of Epidemiology Koch's Postulates Investigating Clusters of Parkinson's Disease Kuru and Creutzfeldt-Jakob Disease Does Smoking Cause Parkinson's Disease? Causation versus Association-The Hill Criteria Epidemiology of Smoking and Parkinson's Disease Pesticides, Head Trauma, and Parkinson's Disease Parkinson's at the Manor 4. CAUSES OF PARKINSON'S DISEASE Does an Infection Cause Parkinson's Disease? When Prophecy Fails Do Toxins Cause Parkinson's Disease? An Answer from the Frozen Addicts Do Genes Cause Parkinson's Disease? All Disease Is Genetic Disease 5. MEDICATIONS FOR PARKINSON'S DISEASE The Herbal Tradition Herbal Treatment of Parkinson's Disease Awakenings-L-Dopa Therapy Dopamine and Schizophrenia-The Dopamine Receptor Rational Drug Therapy-Trying to Prevent Progression of Parkinson's Disease Coenzyme Q10-Another Quest for Neuroprotection The Challenges of Taking L-Dopa 6. IMAGES OF THE BRAIN-A PICTURE OF THE BRAIN IS WORTH A THOUSAND WORDS Imaging and Diagnosis Imaging and Presymptomatic Diagnosis Imaging and Disease Progression 7. A BETTER MODEL OF PARKINSON'S DISEASE Dopamine Nerve Cells Connect to Many Parts of the Brain Dopamine is One of Many Neurotransmitters That Are Important in Parkinson's Disease Patients with Parkinson's Disease Lose Cells from Many Areas of the Brain 8. BRAIN SURGERY FOR PARKINSON'S DISEASE Can Destroying Part of the Brain Be Good? "Brain Transplantation"-Implanting New Brain Cells Gene Therapy 9. LIVING WITH PARKINSON'S DISEASE Mood, Behavior, and Parkinson's Disease Can L-Dopa Make People Gamble? Are Parkinson's Disease and Alzheimer's Disease Related? Sleep and Parkinson's Disease Fall and Injury Prevention 10. CONCLUSIONS What Happens to Brain Cells to Cause Parkinson's Disease? Living Better with Parkinson's Disease The Story of Parkinson's Disease Is Not Finished Appendix: Reading about Parkinson's Disease Glossary Notes Index
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