Understanding the Process of Aging

The Roles of Mitochondria: Free Radicals, and Antioxidants
Herausgeber: Packer, Lester

• Broschiertes Buch

Produktbeschreibung

This innovative reference explores a wide selection of topics associated with aging, providing a solid understanding of the significance and molecular basis of the aging process and charting the course of future research in the area. Stresses the interplay of mitochondria, mitochondrial DNA, oxidants, and antioxidants! Featuring the research of over 55 experts in the area, Understanding the Process of Aging 1. covers the functions of nitric oxide and peroxynitrite in mitochondria 2. integrates several views on the role of mitochondria in the development of apoptosis 3. gives a quantitative analysis of mutations of mitochondrial DNA during human aging 4. highlights mitochondrial free radical production 5. introduces new roles of ubiquinone in mitochondrial functions 6. offers new antioxidant-based complementary therapeutic strategies 7. details aspects of intact cells and whole organisms in health and disease 8. and more! Featuring over 1800 references, tables, drawings, and photographs, Understanding the Process of Aging benefits nutritionists and dieticians, geriatricians, cell and molecular biologists, chemists and biochemists, pharmacologists, biotechnologists, neurologists, cardiologists, oncologists, dermatologists, and graduate and medical school students in these disciplines.

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Produktdetails

• Verlag: Taylor & Francis Ltd (Sales)
• Seitenzahl: 384
• Erscheinungstermin: 19. September 2019
• Englisch
• Abmessung: 231mm x 155mm x 20mm
• Gewicht: 590g
• ISBN-13: 9780367399993
• ISBN-10: 0367399997
• Artikelnr.: 57815816

Autorenporträt

Enrique Cadenas, Lester Packer

Inhaltsangabe

The Mitochondrial Production of Oxygen Radicals and Cellular Aging
Alberto Boveris
Lidia E. Costa
and Enrique Cadenas Walking a Tightrope: The Balance Between Mitochondrial Generation and Scavenging of Superoxide Anion
David M. Guidot and Joe M. McCord The Biochemistry of Nitric Oxide and Peroxynitrite: Implications for Mitochondrial Function
Rakesh P. Patel
Trudy Cornwell
and Victor M. Darley-Usmar Oxygen-Dependent Regulation of Biological Functions by Nitric Oxide
Kozo Utsumi
Yoshiki Takehara
Yoko Inai
Munehisa Yabuki
Tomoko Kanno
Manabu Nishikawa
Eisuke F. Sato
and Masayasu Inoue Production of Reactive Oxygen Species in Mitochondria and Age-Associated Pathophysiology: A Reality Check
Henry Jay Forman and Angelo Azzi Functional Roles of Ubiquinone
Jeffery R. Schultz and Catherine Freitag Clarke Mitochondrial Generation of Reactive Oxygen Species and Oxidative Damage During Aging: Roles of Coenzyme Q and Tocopherol
Rajindar S. Sohal
Achim Lass
Liang-Jun Yan
and Linda K. Kwong Mitochondria and Aging: The Mouse's Tale
Steve Esworthy Mitochondria and Apoptosis
Bernard M. Babior
Roberta A. Gottlieb
and Christoph Richter Role of Mitochondria in Oxidative Stress Associated with Aging and Apoptosis: Studies in Intact Cells
Juan Sastre
Federico V. Pallardó
José García de la Asunción
Miguel A. Asensi
Juan M. Esteve
and José Viña-Ribes The Role of Iron and Mitochondria in Aging
Patrick B. Walter
Kenneth B. Beckman
and Bruce N. Ames The Mitochondrial-Lysosomal Axis Theory of Cellular Aging
Ulf T. Brunk and Alexei Terman Quantitative Analysis of Mutations of Mitochondrial DNA During Human Aging
Jörg Napiwotzki
Annette Reith
Andreas Becker
Sandra Leist
and Bernhard Kadenbach Oxidative Damage and Fragility of Mitochondrial DNA
Takayuki Ozawa Mitochondria in Cellular Aging and Degeneration
Gino A. Cortopassi and Alice Wong Mitochondrial Alteration in Aging and Inflammation: A Possible Site of A