The book Universal Serial Bus Port Device Protection Circuit-A Practical Approach is having three chapters. First Chapter discusses in details on development of USB devices and their practical application. Data transfer speed of USB 2.0 & 3.0 from external USB devices to Desktop or portable computer and vice-versa are also included. Second chapter is about discrete components used in short circuit protection of USB devices and their identification, operating and testing procedure on the sensible ground. Third chapter proposes circuit to prevent short circuit, over voltage, over current and Electro-Static Discharge(ESD) protection with the help of discrete components,IC s, Polyzen and SMD devices. A comparative study and technical benefit of USB 2.0 & USB 3.0 is also included for the benefit of the readers. Another important feature of the book is introduction of various electronic components. Author tried to make this book more practical oriented utilizing his 8 years of practical teaching experiences at various levels. This book will be useful for practitioners since the tools and technique required for detection of faulty USB port is explain in details in this book