Urinary tract infections (UTIs) are some of the most common bacterial infections, affecting 150 million people each year worldwide. The societal costs of these infections, including health care costs and time missed from work, are approximately US$3.5 billion per year in the United States alone. The variation in urinary tract virulence reflects the ability of bacteria to trigger mucosal and systemic host responses. Through different molecular interactions, bacteria may trigger epithelial cell responses, cause cell detachment, and invade or kill cells by apoptosis. immunological and hematological branches correlation with UTI are promising in the detection, treatment, and prevention of UTI.