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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The mucous membrane immediately behind the internal urethral orifice presents a slight elevation, the uvula of urinary bladder, caused by the middle lobe of the prostate. The internal urethral orifice is the opening of the urinary bladder into the urethra. It is placed at the apex of the trigonum vesicae, in the most dependent part of the bladder, and is usually somewhat crescent-shaped; the mucous membrane immediately behind it presents a slight elevation in males, the uvula vesicae, caused by the middle lobe of the prostate.