VEGF in Development

Herausgegeben:Ruhrberg, Christiana

• Broschiertes Buch

Produktbeschreibung

his book is devoted to vascular endothelial growth factor A (VEGF his book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for or VEGFA), a secreted signalling protein of great significance for T development and disease in vertebrates. VEGFAcontrols the prolif Tdevelopment and disease in vertebrates. VEGFA controls the prol- eration, eration, migration migration, , specialisatio specialisation n and and surviva survival l of vascula ofvascular r endothelia endothelial l cells, cells, and and iit t isis therefor therefore e essentia essential l for th for e establishmen the establishment t of a functiona ofa functional l blood vesse blood l vessel circuit. circuit. IIn n addition addition, , VEGF VEGFA A is emergin is emerging g as a versatil as a versatile e patternin patterning g factor fofactor r for several several non endothelia non-endothelial l celcell l type types s in vertebrates in vertebrates. . ThusThus, , it playit s a centra plays al rol central e role during organ development at multiple levels, including blood vessel growth, duringorgan developmentat multiple levels, including blood vessel growth, vessel-mediated vessel mediated orga organ n inductio induction n andand tissutissue e differentiation differentiation. . The The discover discovery y ofof non endothelia non-endothelial l rolesroles for VEGF for VEGFA A initiallinitially y came ascarne a as a surprise. surprise.

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Produktdetails

• Molecular Biology Intelligence Unit
• Verlag: Landes Bioscience / Springer / Springer New York / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4419-2693-7
• Softcover reprint of hardcover 1st ed. 2008
• Seitenzahl: 120
• Erscheinungstermin: 19. November 2010
• Englisch
• Abmessung: 248mm x 165mm x 7mm
• Gewicht: 218g
• ISBN-13: 9781441926937
• ISBN-10: 1441926933
• Artikelnr.: 32214817

Inhaltsangabe

The Biology of Vascular Endothelial Cell Growth Factor Isoforms.- VEGF Receptor Signalling in Vertebrate Development.- VEGF Gene Regulation.- Embryonic Vasculogenesis and Hematopoietic Specification.- Role of VEGF in Organogenesis.- VEGF and Endothelial Guidance in Angiogenic Sprouting.- Vascular and Nonvascular Roles of VEGF in Bone Development.- VEGF in the Nervous System.