Vernonia anthelmintica (L.) Willd., more commonly known as kalijiri or bitter cumin, is a member of the Asteraceae family and is used to treat a wide range of conditions, including inflammation, fungal disease, arthritis, fever, pain, filaria, malaria, cancer, depression, and more, according to numerous ethnomedical treatises.Current research on V. anthelmintica encompasses botany, ethnopharmacological applications, phytochemistry, pharmacological evaluations, and patented extracts. Over 115 secondary metabolites, including steroids and flavonoids, have been identified. Among plant parts, the seed showcases the majority of health benefits compared to the stem, bark, leaf, fruit, and root. Utilizing crude extracts and isolated constituents offers diverse medical applications, addressing conditions such as diabetes, fever, inflammation, microbial diseases, arthritis, pain, depression, filaria, malaria, cancer, and wound healing. Studies on acute oral toxicity indicate a safe limit of 2000 mg/kg for various crude extracts. This book explores future research perspectives and opportunities to guide further exploration in areas requiring additional investigation.
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