Gebundenes Buch

Viruses, Genes, and Cancer

Beschreibung

This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor suppressor genes - in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

Autor

Eric Hunter, PhD, is a Professor of Pathology and Laboratory Medicine and a Georgia Research Alliance Eminent Scholar, based in Atlanta, GA, USA Klaus Bister, PhD, is a Professor Emeritus of Biochemistry of University of Innsbruck, Austria, and a Professor Adjunct of The Scripps Research Institute, La Jolla, CA, USA  

Produktdetails

• Current Topics in Microbiology and Immunology 407
• Verlag: Springer / Springer International Publishing / Springer, Berlin
• Artikelnr. des Verlages: 978-3-319-61803-6
• 1st edition 2017
• Seitenzahl: 236
• Erscheinungstermin: 6. September 2017
• Englisch
• Abmessung: 241mm x 160mm x 19mm
• Gewicht: 467g
• ISBN-13: 9783319618036
• ISBN-10: 3319618032
• Artikelnr.: 48321462