This study is a prospective interventional study including one hundred and fifty girls 90 of them complaining of some symptoms of PCOS (irregular menstruation, acne, hirsutism ), from (EL-Mahalla secondary school for girls, also from cosmotic laser center ) in the period between June 2017 and december 2017. and detect the effect of calcium and vitamin d on these patients and symptoms of pco after councelling every patients about the nature of study and the regimen of treatment.