Vitamin A Metabolism and Kinetics During the Neonatal Period
Studies in the Rat Model
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The purpose of the project described in this book was to determine the uptake, retention, and distribution of vitamin A in tissues of neonatal rats, without and after supplementation with vitamin A in the amount equivalent to that which has been given to human infants. The results have shown that vitamin A retention in peripheral tissues of neonates is poor leading to its extensive recycling between plasma and tissues prior to excretion. These findings have important implications for the vitamin A supplementation programs conducted in low-income countries to combat child mortality.
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