Vitamin D

Oxidative Stress, Immunity, and Aging
Herausgeber: Gombart, Adrian F

• Broschiertes Buch

Produktbeschreibung

Vitamin D insufficiency/deficiency is a worldwide, public health problem in both developed and developing countries. This volume highlights the most recent research findings on the impact of this nutrient in oxidative stress, immunity, and aging. The book examines vitamin D's genomic and nongenomic effects, the role of therapeutic analogs in treating disease, and the production of vitamin D by the body. It discusses its role in modulating oxidative stress and regulating the immune response as well as its role in the regulation of the aging process.

Produktdetails

• Verlag: CRC Press
• Seitenzahl: 462
• Erscheinungstermin: 16. November 2016
• Englisch
• Abmessung: 254mm x 178mm x 24mm
• Gewicht: 798g
• ISBN-13: 9781138199446
• ISBN-10: 1138199443
• Artikelnr.: 57039965

Autorenporträt

Adrian F. Gombart received a Ph.D. degree in microbiology from the University of Washington. For many years, he was an assistant and associate professor at Cedars-Sinai Medical Center and the David Geffen School of Medicine at the University of California, Los Angeles, in the Department of Biomedical Sciences and Division of Hematology and Oncology. He is currently a principal investigator in the Linus Pauling Institute and an associate professor in the Department of Biochemistry and Biophysics at Oregon State University. Dr. Gombart is a member of the American Society for Hematology and the Society for Leukocyte Biology. Dr. Gombart's research interests focus on the role of vitamin D in the innate immune response against infection. His laboratory studies the regulation of antimicrobial peptide gene expression by vitamin D and other nutritional compounds. He was recognized for his contributions to the field of vitamin D and immunity, with a Young Investigator Award from the Vitamin D Workshop in 2005.

Inhaltsangabe

Vitamin D: An Overview. Vitamin D: A Fountain of Youth in Gene Regulation.
Vitamin D Receptor: Genomic and Epigenomic Effects. Vitamin D Analogs and
Their Clinical Uses. Extrarenal CYP27B1 and Vitamin D Physiology.
Oxidative Stress. Vitamin D and Oxidative Stress. Vitamin D3 Upregulated
Protein 1 (VDUP1): Roles in Redox Signaling and Stress-Mediated Diseases.
Vitamin D and Its Role in Photoprotection of the Skin. Vitamin D and
Adipose Tissue: 1¿, 25-Dihydroxyvitamin D3 (Calcitriol) Modulation of
Energy Metabolism, Reactive Oxygen Species, and Inflammatory Stress.
Membrane Receptors for Vitamin D Metabolites and the Role of Reactive
Oxygen Species. Immunity and Disease. Vitamin D and Human Innate Immunity.
Vitamin D and Autoimmune Disease. Vitamin D: Anti-Inflammatory Actions to
Prevent and Treat Diseases. Vitamin D and Infection. Aging. Potential Role
of Vitamin D and Fibroblast Growth Factor 23-Klotho System in Aging.
Vitamin D and Cardiovascular Disease. Vitamin D, Aging, and Chronic
Diseases. Vitamin D: Defending the Aging Nervous System. Index.