Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The Vroman effect, named after Leo Vroman, is exhibited by protein adsorption to a surface by blood serum proteins. The highest mobility proteins arrive first and are later replaced by less motile proteins that have a higher affinity for the surface. A typical example of this occurs when fibrin adheres to a biopolymer surface and is later replaced by other proteins. This results in a depletion overall of blood serum levels of fibrinogen.