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The Water of Life is a fictional drug from Frank Herbert's science fiction Dune universe.In Terminology of the Imperium, the glossary of the 1965 novel Dune, Herbert provided the following definition: WATER OF LIFE: an "illuminating" poison ... Specifically, that liquid exhalation of a sandworm ... produced at the moment of its death from drowning which is changed within the body of a Reverend Mother to become the narcotic used in the sietch tau orgy. An "awareness spectrum" narcotic.While "Water of Life" is the term used by the native Fremen of the planet Arrakis, the substance is referred to as spice essence by the Bene Gesserit and other groups starting in Dune Messiah (1969), the second novel in the series. Described as a blue liquid in Children of Dune (1976), the drug is noted in Chapterhouse: Dune (1985) to possess the "pungent odor" of "bitter cinnamon" associated with melange, the other, more important by-product of the sandworm life cycle.