The broad overview of writing uncovered that WS is a significant wellspring of numerous pharmacologically and restoratively significant synthetic compounds, for example, Withaferins, sitoindosides and different valuable alkaloids. In Indian assortment thirteen Dragendroff positive alkaloids have been accounted for. The withanolides are the most looked through compound constituents of WS and till date around 138 withanolides with both beta and side chain has been accounted for separated from different amino corrosive and other typical plant constituents. The plant has additionally been generally read up for their different pharmacological exercises like cancer prevention agent, anxiolytic, adaptogen, memory improving, antiparkinsonian, counter-agent, mitigating, antitumor properties. Different impacts like immunomodulation, hypolipidemic, antibacterial, cardiovascular assurance, sexual way of behaving, resistance and reliance have additionally been contemplated. Albeit the outcomes from this survey are very encouraging for the utilization of WS as a multi-reason restorative specialist, a few impediments right now exist in the ongoing writing.