In an economic context where many paradigms are being challenged, where more and more managers and employees feel that they are making a big difference between what is asked of them and their personal values, where constant changes in strategy are becoming the new norm, where the line between personal and professional life is increasingly subjective and fluctuating, the quest for meaning takes on its full meaning! On the basis of this premise, we questioned the organisational and managerial models at work within companies, the modes of governance, the levers of social innovation to be put in place to promote the well-being of employees, etc. As economic performance is no longer the only scale of value to be taken into consideration, HR issues are at the heart of the virtuous circle that exists between fulfilment at work (commitment, motivation, well-being) and the sustainable performance of companies.