Most forms of the disease states begin with cell injury and consequent loss of cellular function. Cell injury is defined as a variety of stresses, a cell encounters as a result of changes in its internal and external environment.Wound healing is a complex but generally orderly process. Sequential waves of specialized cell types first clear the inciting injury and then progressively build the scaffolding to fill in any resulting defect. The events are orchestrated by an interplay of soluble growth factors.The general principles of healing and the cellular and molecular events observed in non-oral sites, also apply to healing processes that take place following periodontal treatment.It is important to mention that these various phases of wound healing overlap somewhat in in time. In this book an attempt has been made to collect the available literature pertaining to wound healing related to various periodontal treatment modalities.