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High Quality Content by WIKIPEDIA articles! Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP. It is a ribonucleoside monophosphate. Xanthylic acid can be used in quantitative measurements of the inosine monophosphate dehydrogenase enzyme activities in purine metabolism, as recommended to ensure optimal thiopurine therapy for children with acute lymphoblastic leukaemia (ALL). Many organisms have metabolic pathways to synthesize and break down purines. Purines are biologically synthesized as nucleotides (bases attached to ribose 5-phosphate). The committed step is amidophosphoribosyltransferase.