Strychnine and picrotoxin were tested as possible antagonists of two puta tive inhibitory transmitters in the retina: taurine and GABA, Strychnine was shown to antagonize the depressive action of taurine on the ERG b-wave, but it did not affect the depressive action of GABA. Conversely, picrotoxin had no effect on the depressive action of taurine on the ERG b-wave, but it antagonizes to some extent the depressive effect of GABA. These data, as well as those obtained through recording tectal evoked responses, lead to the conclusion that taurine and GABA do not act in the same way in retinal…mehr
Strychnine and picrotoxin were tested as possible antagonists of two puta tive inhibitory transmitters in the retina: taurine and GABA, Strychnine was shown to antagonize the depressive action of taurine on the ERG b-wave, but it did not affect the depressive action of GABA. Conversely, picrotoxin had no effect on the depressive action of taurine on the ERG b-wave, but it antagonizes to some extent the depressive effect of GABA. These data, as well as those obtained through recording tectal evoked responses, lead to the conclusion that taurine and GABA do not act in the same way in retinal inhibitory synaptic transmission. REFERENCES CURTIS, D.R., AW. DUGGAN & G.A.R. JOflNSTON. Glycine, strychnine, picro toxine and spinal inhibition. Brain Res. 14, 759-762 (1969). CURTIS, D.R., L. HOSLI & G.AR. JOHNSTON. A pharmacological study of the depression of spinal neurones by glycine and related aminoacids. Exp. Brain Res. 6, 1-18 (1968 a). CURTIS, D.R., L.HOSLI, G.A.R. JOHNSTON & LH. JOHNSTON. The hyperpolariza tion of spinal motoneurones by glycine and related aminoacids. Exp. Brain Res. 5, 235-258 (1968 b). CURTIS, D.R. & A.K. TEBECIS. Bicuculline and thalamic inhibition. Exp. Brain Res. 16,210-218 (1972). DA VIDSON, N. & H. REISINE. Presynaptic inhibition in cuneate blocked by GABA antagonists. Nature New Biology 234,223-224 (1971).Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Ultrastructure and micro-electrophy-siology of the macula.- Normal and abnormal visual pathways and the cortical representation of the visual field.- Data analysis of electrophysiological signals.- Macular electro-oculography.- The examination of the foveolar and perifoveolar function with the aid of flicker fusion thresholds and flicker Erg responses.- Erg and Eog diagnosis and prognosis of bull's eye maculopathy.- Clinical and electrophysiological findings of a case of fundus flavimaculatus.- A pattern stimulus for optimal response from the retina.- Topographical analysis of the pattern evoked response (Per): Its application to the study of macular and peripheral vision in normal people and in some pathological cases.- Electro-Ophthalmology in senile macular degenerations.- Some results on mathematical analysis of dynamic ERG.- Calculation of glare effect.- Preliminary attempt at a digital processing of the electro-oculogram (EOG): Application to a spatio-temporal time and space analysis of saccadic eye movements during free search.- Time constant of the decay process of both ERG and VER at the off-set of stimulation.- Statistical discrimination between visual evoked responses according to photostimulus wavelength.- Dynamic electroretinography in monochromatic lights and fluorescence electroretinography in lemurs.- Behaviour of the ganglion cells of the frog's retina submitted to a polarizing current: an in vivo study.- ERG photometry in goldfish by the criterion response method.- Contribution to the study of ocular interdependence by electro-oculo-graphy.- Contralateral effect in the electro-oculogram: Experimental verification and clinical implications.- Recent data on two putative inhibitory transmitters in the retina: Tourine and Gaba.- Increased size ofB-wave in the rabbit after intravenous diphenylhydantoin.- Preservation of ERG in the isolated perfusing eye by fluorocarbon as the erythrocyte substitute.- The effects of glycine on the rabbit retina averaged ERG and microscopic anatomy.- Azide poisoning: Its effects on P III resting potential of the isolated retina.- C-wave amplitude oscillations in the sheep ERG.- In tensity-Amplitude relationship and cyclic variations of the C-wave of the human D.C. registered ERG.- The effect of barbiturate on the C-wave of the electroretino-gram and the standing potential of the sheep eye.- The effect of elevated intraocular pressure on the human ERG and VER.- Paravenous pigmentary retinopathy.- A comparison of electroretinographic and dark adaptation studies in retinitis pigmentosa.- Tapeto-choroidal atrophy.- The oscillatory potentials of the ERG in Oguchi's disease.- The influence of myopia on the EOG.- ERG in cases of therapeutic light coagulation.- ERG and EOG-results in toxocara canis retino chorioiditis.- Effect of stimulus duration on the oscillatory potentials of the human electro-retinogram.- Sensory and electrocortical determination of the area-luminance relationship in response to intermittent light stimulation in man.- Ocular dipole moment (ODM) - Variation excited by photo-flash.- The slow dark oscillation of the ocular dipole moment (ODM) -Dependence upon the amplitude of the step to darkness.- Electrophysiological and psychophysical examinations of a family with progressive cone dystrophy.- Visual evoked response and antimalarial drugs.- Comparative electrophysiological observations of intraocular tumours and retinal detachments.- The macular function in the ERG.
Ultrastructure and micro-electrophy-siology of the macula.- Normal and abnormal visual pathways and the cortical representation of the visual field.- Data analysis of electrophysiological signals.- Macular electro-oculography.- The examination of the foveolar and perifoveolar function with the aid of flicker fusion thresholds and flicker Erg responses.- Erg and Eog diagnosis and prognosis of bull's eye maculopathy.- Clinical and electrophysiological findings of a case of fundus flavimaculatus.- A pattern stimulus for optimal response from the retina.- Topographical analysis of the pattern evoked response (Per): Its application to the study of macular and peripheral vision in normal people and in some pathological cases.- Electro-Ophthalmology in senile macular degenerations.- Some results on mathematical analysis of dynamic ERG.- Calculation of glare effect.- Preliminary attempt at a digital processing of the electro-oculogram (EOG): Application to a spatio-temporal time and space analysis of saccadic eye movements during free search.- Time constant of the decay process of both ERG and VER at the off-set of stimulation.- Statistical discrimination between visual evoked responses according to photostimulus wavelength.- Dynamic electroretinography in monochromatic lights and fluorescence electroretinography in lemurs.- Behaviour of the ganglion cells of the frog's retina submitted to a polarizing current: an in vivo study.- ERG photometry in goldfish by the criterion response method.- Contribution to the study of ocular interdependence by electro-oculo-graphy.- Contralateral effect in the electro-oculogram: Experimental verification and clinical implications.- Recent data on two putative inhibitory transmitters in the retina: Tourine and Gaba.- Increased size ofB-wave in the rabbit after intravenous diphenylhydantoin.- Preservation of ERG in the isolated perfusing eye by fluorocarbon as the erythrocyte substitute.- The effects of glycine on the rabbit retina averaged ERG and microscopic anatomy.- Azide poisoning: Its effects on P III resting potential of the isolated retina.- C-wave amplitude oscillations in the sheep ERG.- In tensity-Amplitude relationship and cyclic variations of the C-wave of the human D.C. registered ERG.- The effect of barbiturate on the C-wave of the electroretino-gram and the standing potential of the sheep eye.- The effect of elevated intraocular pressure on the human ERG and VER.- Paravenous pigmentary retinopathy.- A comparison of electroretinographic and dark adaptation studies in retinitis pigmentosa.- Tapeto-choroidal atrophy.- The oscillatory potentials of the ERG in Oguchi's disease.- The influence of myopia on the EOG.- ERG in cases of therapeutic light coagulation.- ERG and EOG-results in toxocara canis retino chorioiditis.- Effect of stimulus duration on the oscillatory potentials of the human electro-retinogram.- Sensory and electrocortical determination of the area-luminance relationship in response to intermittent light stimulation in man.- Ocular dipole moment (ODM) - Variation excited by photo-flash.- The slow dark oscillation of the ocular dipole moment (ODM) -Dependence upon the amplitude of the step to darkness.- Electrophysiological and psychophysical examinations of a family with progressive cone dystrophy.- Visual evoked response and antimalarial drugs.- Comparative electrophysiological observations of intraocular tumours and retinal detachments.- The macular function in the ERG.
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