Kris is a man in his prime and an amicably divorced family father with two adult daughters who adore him. His career as a renowned pathologist is as flawless as his work-life balance - except for the nagging sensation that he is not inhabiting the appropriate body. He has not lived out his clandestine transsexual proclivity except on sporadic occasions. Taking a sabbatical, he has been eagerly awaiting, he undergoes a routine medical check and is caught off guard by the devastating diagnosis of prostate cancer. He decides to go on a journey to figure out whether or not he wants to live his remaining life as a woman and how people will react to his coming out. On his trip, he is surprised by controversial experiences-his perplexed brother, the unforeseen hostility of a student buddy, unexpected support of his trans identity by an escort girl who turns out to be a friend. Most of all, he is stunned by Chloé, formerly Leopold, who becomes his mentor and with whom he obsessively falls in love. Y's Revenge is a committed plea for diversity and demonstrates that one's chromosomes do not actually define one's true self.