Accurate Results in the Clinical Laboratory (eBook, ePUB)

A Guide to Error Detection and Correction
Redaktion: Dasgupta Ph. D, Dabcc; Sepulveda MD

• Format: ePub

Produktbeschreibung

Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, Second Edition, provides a comprehensive review of the factors leading to errors in all areas of clinical laboratory testing. This trusted guide addresses interference issues in all laboratory tests, including patient epigenetics, processes of specimen collection, enzymes and biomarkers. Clinicians and laboratory scientists will both benefit from this reference that applies discussions to both accurate specimen analysis and optimal patient care. Hence, this is the perfect reference for clinical laboratorians, from trainees, to experienced pathologists and directors.

• Provides comprehensive coverage across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing
• Includes new case studies that highlight clinical relevance and errors to avoid
• Highlights the best titles published within a variety of medical specialties
• Reviewed by medical librarians and content specialists, with key selections compiled in their annual list

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 510
• Erscheinungstermin: 20. Juli 2019
• Englisch
• ISBN-13: 9780128137772
• Artikelnr.: 61688948

Inhaltsangabe

Section I: Sources of errors in clinical laboratories: An overview 1.
Variation, errors, and quality in the clinical laboratory 2. Errors in
patient preparation, specimen collection, anticoagulant and preservative
use: how to avoid such pre-analytical errors 3. Sample processing and
specimen misidentification issues: major sources of pre-analytical errors
4. Effect of patient-related factors on clinical laboratory test results 5.
Interferences of hemolysis, lipemia and high bilirubin on laboratory tests
6. Immunoassay design 7. Overview of other sources of interferences in
immunoassays: prozone effect and interferences from heterophilic antibodies
and autoantibodies 8. Biotin interference in clinical laboratory tests:
sporadic problem or a serious clinical issue?
Section II: Sources of errors in clinical chemistry laboratory 9.
Challenges in routine clinical chemistry testing analysis of small
molecules 10. Challenges in routine clinical chemistry analysis: proteins
and enzymes 11. Challenges in endocrinology testing 12. Pitfalls in testing
for common tumor markers
Section III: Sources of errors in therapeutic drug monitoring and
toxicology 13. Issues of interferences in therapeutic drug monitoring 14.
Limitations of immunoassays for screening of drugs of abuse in urine:
issues of false positive and false negative results 15. Challenges in
confirmation testing for drugs of abuse 16. Issues of false negative
results in toxicology: difficult in detecting certain drugs and issues with
detection of synthetic cathinone (bath salts), synthetic cannabinoids
(spice), and other new psychoactive substances 17. Ethanol determination
using automated analyzers: limitations and pitfalls
Section IV: Herbal medicines and laboratory testings 18. Effects of herbal
supplements on clinical laboratory test results
Section V: Sources of errors in immunology laboratory 19. Critical issues
in hemoglobinopathy detection and serology testing for HIV and hepatitis
infections 20. Sources of errors in immunology and serology testing
Section VI: Sources of errors in molecular, genetic and related testings
21. Sources of error in molecular diagnostic analyses 22. Molecular testing
for targeted therapies and pharmacogenomics 23. Challenges and sources of
inaccuracy in biochemical genetics testing
Section VII: Sources of errors in microbiology testings 24. Sources of
pre-analytical, analytical and post-analytical errors in the microbiology
laboratory
Section VIII: Sources of errors in hematology and coagulation testings 25.
Sources of errors in hematology testing 26. Sources of errors in
coagulation testing 27. Sources of errors in flow cytometry
Section IX: Sources of errors in transfusion medicine 28. Interferences in
blood bank testing 29. Errors and adverse effects of blood transfusion 30.
Methodological issues in point of care testing devices 31. Special concern:
sources of inaccuracy in breath alcohol analysis