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This textbook begins with a concise introduction on the various, most common clinical presentations of acute coronary syndromes (ACS). Then it presents a compact list of antiplatelet agents and anticoagulant therapy, followed by the presentation of the most common bleeding complications in the various clinical settings. Furthermore, it presents the essential elements for symptomatic management of acute STEMI, NSTEMI and of UA according to current guidelines. Finally, it discusses the novel strategies for early discharge and subsequent follow-up, dealing specifically with long-term association of antiplatelet agents and anticoagulants after ACS and with an updated strategy for the correction of risk factors. Physicians confronted with patients with ACS will find useful guidelines in this volume as well as the rationale, from which they have been developed and proposed.