Ruimao Hua

Addition Reactions with Unsaturated Hydrocarbons (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Addition Reactions with Unsaturated Hydrocarbons

Provides comprehensive coverage of the atom-economic approach to functionalized molecules using unsaturated hydrocarbons as starting materials

Unsaturated hydrocarbons have emerged as an important class of fundamental starting materials in organic synthesis. Synthetic methodologies incorporating unsaturated hydrocarbons continue to expand due to their numerous applications in the synthesis of a vast array of chemicals.

Addition Reactions with Unsaturated Hydrocarbons presents an up-to-date overview of modern methods that utilize reactions of unsaturated hydrocarbons as building blocks of organic synthesis, covering the conceptual and practical knowledge required for designing atom-efficient reactions to synthesize functionalized molecules. This authoritative volume discusses homo-dimerization and cross-dimerization of alkynes and/or alkenes, synthesis of carbonyl compounds from the hydration of alkynes, cycloadditions of alkynes and alkenes for the synthesis of carbocycles and heterocycles, double functionalization of alkynes and alkenes by addition reactions of element-element bonds, and more.

• Summarizes the most recent developments in the reactions of unsaturated hydrocarbons
• Features more than 600 schemes describing typical reactions starting from unsaturated hydrocarbons
• Covers topics such as alkynylated reactions, addition and cycloaddition reactions of alkynes and alkenes, and carbonylation of alkynes and alkenes with carbon monoxide
• Includes examples of synthesis procedures of natural products involving alkyne transformation

With comprehensive coverage of important reactions of unsaturated hydrocarbons, Addition Reactions with Unsaturated Hydrocarbons is a valuable resource for organic chemists, pharmaceutical chemists, and biochemists in both academia and industry as well as an excellent reference text for graduate students in relevant areas of chemistry.

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Produktdetails

• Verlag: Wiley-VCH
• Erscheinungstermin: 28. Februar 2022
• Englisch
• ISBN-13: 9783527804825
• Artikelnr.: 63585052

Autorenporträt

Dr. Ruimao Hua is a Professor of Chemistry at the Department of Chemistry, Tsinghua University (TU) in Beijing, China. Having obtained his PhD degree from Tokyo Institute of Technology, he spent six years working at AIST in Japan before taking up his present appointment at TU. Professor Hua has over 110 published scientific papers and more than 120 authorized patents contributing to organic synthetic methodologies and organic materials for displays (liquid crystal display & OLED display). He is also the member of editorial board of several academic journals.

Inhaltsangabe

Chapter 1. Dimerization of Alkynes and Alkenes
1.1 Markovnikov Dimerization of Terminal Alkynes
1.2 anti-Markovnikov (head-to-head) Dimerization of Terminal Alkynes
1.3 Dimerization and Cross-dimerization of Terminal Alkenes
1.4 Cross-Dimerization of Different Alkynes or Alkynes with Alkenes
Chapter 2. Addition of C(sp)-H Bonds to Unsaturated Compounds
2.1 Addition of Terminal Alkynes to Carbonyl Compounds
2.2 Addition of Terminal Alkynes to Alkenes
2.3 Addition of Terminal Alkynes to Imines
2.4 Addition of Terminal Alkynes to Other Compounds
Chapter 3. Functionalized Alkenes from Hydrofunctionalization of Alkynes
3.1 Hydroborations of Alkynes
3.2 Hydrosilylation of Alkynes
3.3 Hydrostannation of Alkynes
3.4 Hydroamination of Alkynes
3.4.1 Hydroamination of alkynes with primary amines
3.4.2 Hydroamination of alkynes with secondary amines
3.4.3 Cyclohydroamination of alkynes
3.4.4 Aminocarbonylation of alkynes
3.5 Hydrophosphination of Alkynes and Related H-P(O) Addition
3.5.1 Hydrophosphination of Alkynes
3.5.2 Addition of PV(O)-H bond to alkynes
3.6 Hydrothiolation of Alkynes
3.6.1 Markovnikov hydrothiolation of alkynes
3.6.2 anti-Markovnikov hydrothiolation of alkynes
3.7 Addition of O-Nucleophiles to Alkynes
3.7.1 Addition of alcohols and phenols to alkynes
3.7.2 Addition of acids to alkynes
Chapter 4. Hydrofunctionalization of Carbon-Carbon Double Bonds
4.1 Hydroboration of Alkenes
4.1.1 Markovnikov hydroboration of alkenes
4.1.2 anti-Markovnikov hydroboration of alkenes
4.1.3 Hydroboration of allenes and 1,3-dienes
4.1.4 Asymmetric hydroboration of alkenes
4.2 Hydrosilylation of Carbon-Carbon Double Bonds
4.2.1 Markovnikov and anti-Markovnikov hydrosilylation of alkenes
4.2.2 Hydrosilylation of allenes
4.2.3 Hydrosilylation of 1,3-dienes
4.2.4 Asymmetric hydrosilylation of alkenes
4.3 Hydrostannation of Carbon-Carbon Double Bonds
4.4 Hydroamination of Carbon-Carbon Double Bonds
4.4.1 Markovnikov hydroamination of alkenes
4.4.2 anti-Markovnikov hydroamination of alkenes
4.4.3 Hydroamination of allenes and 1,3-dienes
4.4.4 Asymmetric hydroamination of alkenes
4.4.5 Nitrogen-heterocycles from intramolecular hydroamination of alkenes
4.5 Hydrophosphination of Alkenes and Related PV(O)-H Addition
4.6 Hydrothiolation of Carbon-Carbon Double Bonds
4.7 Addition of O-Nucleophiles to Alkenes
Chapter 5. Double Functionalization of Alkynes and Alkenes by Addition of Element-Element Bonds
5.1 Addition Reaction of Group 13 Element-Element Bonds
5.1.1 cis-Addition reactions to alkynes
5.1.2 trans-Addition reactions to alkynes
5.1.3 Addition reactions to alkenes
5.1.4 Synthesis of 1,1-diborylalkanes/alkenes via addition of B-B bond
5.2 Addition Reaction of Group 14 Element-Element Bonds
5.3 Addition Reaction of Group 15 Element-Element Bond
5.4 Addition Reactions of Group 16 Element-Element Bond
5.4.1 cis-Addition reactions to alkynes
5.4.2 trans-Addition reactions to alkynes
5.4.3 Different heteroatom bond addition reactions to alkynes
5.4.4 Addition reactions to alkenes
5.5 Addition Reactions of Element-Element Bonds from Different Group Heteroatoms
5.5.1 cis-Addition reactions to alkynes
5.5.2 trans-Addition reactions to alkynes
5.5.3 Addition reactions to alkenes
Chapter 6. Double Functionalization of Alkynes by Addition of Carbon-Element Bonds
6.1 Addition Reactions of Carbon-Group 13 Bonds
6.2 Addition Reactions of Carbon-Group 14 Bonds
6.2.1 Addition reactions of carbon-silicon bonds
6.2.2 Addition reactions of carbon-germanium bonds
6.2.3 Addition reactions of carbon-tin bonds
6.3 Addition Reactions of Carbon-Group 15 Bonds
6.4 Addition Reactions of Carbon-Group 16 Bonds
6.4.1 Addition reactions of carbon-oxygen bonds
6.4.2 Addition reaction of carbon-sulfur bonds
6.4.3 Addition reactions of carbon-seleni