Advances in Human Genetics 15 (eBook, PDF)

Redaktion: Harris, Harry

• Format: PDF

Produktbeschreibung

Zur Zeit liegt uns keine Inhaltsangabe vor.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Springer US
• Seitenzahl: 300
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9781461583561
• Artikelnr.: 43993427

Inhaltsangabe

1 Chromosomal Abnormalities in Leukemia and Lymphoma: Clinical and Biological Significance.- Methods.- Chronic Myelogenous Leukemia (CML).- Acute Nonlymphocytic Leukemia (ANLL) de Novo.- Acute Nonlymphocytic Leukemia Induced by Treatment.- Acute Lymphocytic Leukemia (ALL).- Malignant Lymphoma (ML).- The Biological Significance of Consistent Chromosomal Abnormalities.- References.- 2 An Algorithm for Comparing Two-Dimensional Electrophoretic Gels, with Particular Reference to the Study of Mutation.- The Theory and Practice of Two-Dimensional Gels, with Particular Reference to the Study of Mutation.- The General Problem of Image Comparison.- A Set of Algorithms for Detecting Potential Mutational Events.- Validation of the Current Algorithm.- Improving the System: Necessary Developments in the Algorithm.- Improving the System: Necessary Developments in Two-Dimensional Gels.- Experimental Validation of This Approach.- Some Issues in Data Management.- Summary.- Recent Developments.- References.- 3 The Human Argininosuccinate Synthetase Locus and Citrullinemia.- Historical Aspects.- Biology of the Argininosuccinate Synthetase Locus.- Biochemistry of the Enzyme.- Cloning of Human Argininosuccinate Synthetase Gene.- Argininosuccinate Synthetase Pseudogenes.- Citrullinemia-Clinical Aspects.- Molecular Analysis in Citrullinemia.- Molecular and Genetic Analysis of Regulation.- Gene Transfer Using the Argininosuccinate Synthetase Locus.- Future Directions.- References.- 4 Molecular Genetics of the Human Major Histocompatibility Complex.- Characterization of the HLA Genes.- HLA Genes As Probes.- Conclusion.- References.- 5 Genetics of Human Alcohol and Aldehyde Dehydrogenases.- Alcohol Dehydrogenases.- Aldehyde Dehydrogenases.- References.- Addendum.