Somatomedins are considered with regard to bioassays and purification, the mechanism of their production, and their biological action in vitro. The book further tackles growth regulation in cultures of embryonic rat fibroblasts by the serum factors S1 and S2, as well as the endocrine role of the thymus and its hormone, thymosin, in the regulation of the growth and maturation of host immunological competence. The text also encompasses the significance of cyclic GMP in the action of growth-promoting factors. Endocrinologists, biochemists, physiologists, and medical students will find the book invaluable.
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