Allergy and Allergic Diseases (eBook, PDF)

Redaktion: Kay, A. Barry; Kaplan, Allen P.; Holt, Patrick G.; Bousquet, Jean

• Format: PDF

Produktbeschreibung

Reserve your copy now This two volume book is an outstanding reference source on all aspects of allergy and allergic diseases. Covering virtually every allergic condition, from the immunological and molecular basis of the allergic response to future trends in allergic disease prevention, this new international editorial team (A.B.Kay, Jean Bousquet, Pat Holt and Allen Kaplan) have completely revised and updated the text, from both a scientific and clinical perspective. References will continue to be added to the text until it goes to press making this the most up-to-date book available in the field. This second edition consists of more than 1,800 pages contained within 98 chapters. The price includes a fully searchable companion CD ROM with the complete text and over 300 images from the book in full colour.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 2184
• Erscheinungstermin: 26. Januar 2009
• Englisch
• ISBN-13: 9781444300925
• Artikelnr.: 37362641

Autorenporträt

A Barry Kay, National Heart and Lung Institute, London, UK Allan P Kaplan, National Allergy and Asthma Centre, South Carolina, USA Jean Bousquet, Hopital Arnaud dde Villeneuve, Montpellier, France Patrick G Holt, Telethon Institute for Child Health, Perth, Australia

Inhaltsangabe

List of Contributors ix
Foreword xvii
Preface xviii
VOLUME 1 The Scientific Basis of Allergy
Part 1 Immunology of the Allergic Response
1 Allergy and Hypersensitivity: History and Concepts 3
A. Barry Kay
2 Development of Allergy and Atopy 23
Catherine Thornton and Patrick G. Holt
3 T Cells and Cytokines in Asthma and Allergic Inflammation 48
Chris Corrigan
4 Regulatory T Cells and Other Tolerogenic Mechanisms in Allergy and Asthma
83
Catherine Hawrylowicz and Cezmi A. Akdis
5 IgE and IgE Receptors 103
Brian J. Sutton, Andrew J. Beavil, Rebecca L. Beavil, and James Hunt
6 Immunoglobulin Gene Organization and Expression and Regulation of IgE 119
Hannah J. Gould and David J. Fear
7 Environmental Factors in IgE Production 141
Anne Tsicopoulos, Catherine Duez, and Andrew Saxon
8 Antigen-presenting Dendritic Cells and Macrophages 166
Bart N. Lambrecht and Hamida Hammad
9 Innate Immunity in Allergic Disease 187
Ian Sabroe
10 Signal Transduction in Allergic and Inflammatory Cells 203
Rafeul Alam
Part 2 Inflammatory Cells and Mediators
11 Mast Cells: Biological Properties and Role in Health and Allergic
Diseases 217
Peter Bradding and Glenn Cruse
12 Eosinophils: Biological Properties and Role in Health and Disease 258
Simon P. Hogan, Helene F. Rosenberg, Redwan Moqbel, Simon Phipps, Paul S.
Foster, Paige Lacy, A. Barry Kay, and Marc E. Rothenberg
13 Neutrophils: Biological Properties and Role in Health and Allergic
Diseases 295
Alison M. Condliffe, Andrew S. Cowburn, and Edwin R. Chilvers
14 Basophils: Biological Properties and Role in Allergic Diseases 320
Gianni Marone, Giuseppe Spadaro, and Arturo Genovese
15 Leukocyte Adhesion in Allergic Inflammation 337
Michelle J. Muessel and Andrew J. Wardlaw
16 Airway Epithelium 366
Pedro C. Avila and Robert P. Schleimer
17 Airway Vascularity in Asthma 398
John W. Wilson
18 Fibroblasts and the Extracellular Matrix 412
Lynne A. Murray, William G. Glass, Anuk M. Das, and Geoffrey J. Laurent
19 Immune Complexes and Complement: Their Role in Host Defense and in
Disease 436
Michael M. Frank and C. Garren Hester
20 Bradykinin Pathways and Allergic Disease 451
Allen P. Kaplan
21 Chemokines 471
James E. Pease and Timothy J. Williams
22 Neurotrophins 494
Wolfgang A. Nockher, Sanchaita Sonar, and Harald Renz
23 Neuropeptides 511
David A. Groneberg and Axel Fischer
24 Late-phase Allergic Reactions in Humans 524
Yee-Ean Ong and A. Barry Kay
Part 3 Pharmacology
25 Antihistamines 551
F. Estelle, R. Simons, and Keith J. Simons
26 Lipid Mediators: Leukotrienes Prostanoids Lipoxins and
Platelet-activating Factor 566
Sophie P. Farooque, Jonathan P. Arm, and Tak H. Lee
27 Theophylline and Isoenzyme-selective Phosphodiesterase Inhibitors 634
Mark A. Giembycz
28 Adrenergic Agonists and Antagonists 668
Tony R. Bai
29 Cholinergic Antagonists 683
Nicholas J. Gross
30 Antileukotriene Agents 694
Graeme P. Currie and Brian J. Lipworth
31 Glucocorticosteroids 715
Peter J. Barnes
32 Immunomodulating Drugs 732
Iain A.M. MacPhee
Part 4 Physiology
33 Physiologic Aspects of Asthma 749
Philip W. Ind and Neil B. Pride
34 Aerosol Delivery Systems 768
Thomas G. O'Riordan and Gerald C. Smaldone
35 Bronchial Hyperresponsiveness 783
Guy F. Joos
36 Exercise-induced Bronchoconstriction: Animal Models 794
Arthur N. Freed and Sandra D. Anderson
37 Exercise-induced Bronchoconstriction: Human Models 808
Arthur N. Freed and Sandra D. Anderson
38 Sensory and Autonomic Nervous System in Asthma and Rhinitis 823
Bradley J. Undem and Kevin Kwong
39 Mucus and Mucociliary Clearance in Asthma and Allergic Rhinitis 840
Duncan F. Rogers
40 Biology of Vascular Permeability 857
Peter Clark
41 Airway Smooth Muscle 874
Stuart J. Hirst
Part 5 Allergens
42 Biochemistry of Allergens and Recombinant Allergens 895
Rudolf Valenta
43 Host Responses to Allergens 913
Wayne R. Thomas and Belinda J. Hales
44 Allergen Extracts and Standardization 928
Ronald van Ree
45 Grass Tree and Weed Pollen 942
Jean Emberlin
46 Fungi as Allergens 963
Cathryn C. Hassett, W. Elliott Horner, Estelle Levetin, Laurianne G. Wild,
W. Edward Davis, Samuel B. Lehrer, and John Lacey
47 Dust Mites and Asthma 984
Thomas A.E. Platts-Mills and Judith A. Woodfolk
48 Animal Allergens 997
Adnan Custovic and Angela Simpson
49 Airborne Allergens and Irritants in the Workplace 1017
Xaver Baur
50 Allergens from Stinging Insects: Ants Bees and Vespids 1123
Te Piao King and Rafael I. Monsalve
51 Cockroach Allergens Environmental Exposure and Asthma 1131
Martin D. Chapman and Anna Pomés
52 Food Allergens 1146
Ricki M. Helm and A. Wesley Burks
53 Latex Allergy 1164
Robyn E. O'Hehir, Michael F. Sutherland, Alexander C. Drew, and Jennifer M.
Rolland
Part 6 Animal Models of Asthma
54 Primate Models of Allergic Asthma 1187
Charles G. Plopper, Suzette M. Smiley-Jewell, Lisa A. Miller, Michelle V.
Fanucchi, Michael J. Evans, Alan R. Buckpitt, Mark V. Avdalovic, Laurel J.
Gershwin, Jesse P. Joad, Radhika Kajekar, Shawnessy D. Larson, Kent E.
Pinkerton, Laura S. Van Winkle, Edward S. Schelegle, Emily M. Pieczarka,
Reen Wu, and Dallas M. Hyde
55 Airway Remodeling in Small Animal Models 1202
Clare M. Lloyd
56 Are Animal Models of Asthma Useful? 1214
Reinhard Pabst
Index
VOLUME 2 Allergic Diseases: Etiology Diagnosis and Treatment
Part 7 Etiology and Pathology
57 Genetics of Asthma and Atopic Dermatitis 1225
Saffron A.G. Willis-Owen, Miriam F. Moffatt, and William O.C. Cookson
58 Epidemiology of Asthma Atopy and Atopic Disease 1239
Debbie L. Jarvis, Seif O. Shaheen, and Peter Burney
59 The Allergy March 1259
Ulrich Wahn
60 Outdoor Air Pollution and Allergic Airway Disease 1266
Gennaro D'Amato
61 Indoor Air Pollution 1279
Paul Harrison, Rebecca Slack, and Sanjeev Bagga
62 Molecular Immunopathology of Allergic Disease 1290
Susan Foley and Qutayba Hamid
Part 8 Diagnosis of Allergic Disease
63 Principles and Practice of Diagnosis and Treatment of Allergic Disease
1321
Anthony J. Frew and A. Barry Kay
64 Skin Testing in Diagnosis and Management of Respiratory Allergic
Diseases 1335
Pascal Demoly, Anaïs Pipet, and Jean Bousquet
65 Allergy Testing in the Laboratory 1346
Steven O. Stapel and Jörg Kleine-Tebbe
66 Measurement of Markers of Inflammation in Induced Sputum and Exhaled Air
1368
Ian D. Pavord and Dominick E. Shaw
Part 9 Allergic Rhinoconjunctivitis and Immunotherapy
67 Definition and Classification of Allergic Rhinitis and Upper Airways
Diseases 1383
Wytske Fokkens and Jean Bousquet
68 Pathophysiology of Allergic Rhinitis 1402
Peter H. Howarth
69 Management and Treatment of Allergic Rhinitis 1430
Jean Bousquet and Michael A. Kaliner
70 Nasal Polyps and Rhinosinusitis 1454
Wouter Huvenne, Paul Van Cauwenberge, and Claus Bachert
71 Ocular Allergy 1482
Avinash Gurbaxani, Virginia L. Calder, and Susan Lightman
72 Mechanisms in Allergen Injection Immunotherapy 1510
Stephen J. Till and Stephen R. Durham
73 Allergen Injection Immunotherapy: Indications and Practice 1522
Hans-Jørgen Malling
74 Sublingual Immunotherapy 1543
G. Walter Canonica and Giovanni Passalacqua
75 Novel Approaches to Allergen Immunotherapy 1555
Mark Larché
Part 10 Asthma and its Treatment
76 Definition Clinical Features Investigations and Differential Diagnosis
of Asthma 1567
Piero Maestrelli, Gaetano Caramori, Francesca Franco, and Leonardo M.
Fabbri
77 Asthma in Infancy and Childhood 1591
John O. Warner
78 Pathogenesis of Asthma 1608
Stephen T. Holgate
79 Pathology of Asthma 1632
Peter K. Jeffery, A. Barry Kay, and Qutayba Hamid
80 Management of Chronic Asthma 1650
Peter J. Barnes
81 Anti-IgE in Persistent Severe Allergic Asthma 1661
Marc Humbert, Stephen T. Holgate, Howard Fox, and Jean Bousquet
82 Occupational Asthma 1687
Paul Cullinan and Anthony J. Newman Taylor
83 New Drugs for the Treatment of Allergy and Asthma 1712
Trevor T. Hansel, Ed Erin Onn, Min Kon, and Peter J. Barnes
Part 11 Eosinophil-associated Disease and Hypersensitivity Pneumonitis
84 Allergic Bronchopulmonary Aspergillosis 1743
André-Bernard Tonnel, Stéphanie, Pouwels-Frys, and Isabelle Tillie-Leblond
85 Extrinsic Allergic Alveolitis/Hypersensitivity Pneumonitis 1757
Michael C. Zacharisen and Jordan N. Fink
86 Pulmonary Eosinophilia 1779
Jean-François Cordier and Vincent Cottin
87 Hypereosinophilic Syndromes 1802
Hans-Uwe Simon
Part 12 Allergy and the Skin
88 Atopic Dermatitis 1813
Julia D. Proelss and Thomas Bieber
89 Contact Dermatitis 1831
David I. Orton and Carolyn M. Willis
90 Urticaria and Angioedema 1853
Allen P. Kaplan
91 Mastocytosis 1878
Nataliya M. Kushnir-Sukhov, Dean D. Metcalfe, and Jamie A. Robyn
Part 13 Anaphylaxis and Allergy to Food and Drugs
92 Anaphylaxis 1897
M. Rosario Caballero, Stephen J. Lane, and Tak H. Lee
93 Food Allergy and Eosinophilic Gastroenteropathies 1921
Scott H. Sicherer and Hugh A. Sampson
94 Drug Hypersensitivity 1943
Werner J. Pichler
95 Hypersensitivity to Aspirin and other NSAIDs 1966
Andrzej Szczeklik, Ewa NiLankowska-Mogilnicka, and Marek Sanak
96 Insect Sting Allergy 1980
Ulrich R. Müller
Part 14 Prevention of Allergic Disease
97 Prevention of Allergic Disease 1997
Susan L. Prescott and Bengt Björkstén
98 Prevalence of Atopic Disorders in a Developing World: Pitfalls and
Opportunities 2020
Maria Yazdanbakhsh, Taniawati Supali, and Laura C. Rodrigues
Index