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A comprehensive review of the current status of antidepressants - how we arrived at this point in their evolution and where we are going in both the near and the long term. It employs both a scientific and historical approach to accomplish these goals. This volume is intended for practitioners who use antidepressants on a daily basis in their practice as well as for the student and researcher. Each will find that it provides a comprehensive and logical approach to this important group of medications. This book is being published as we mark the end of the first 50 years of the modern antidepressant era.…mehr
A comprehensive review of the current status of antidepressants - how we arrived at this point in their evolution and where we are going in both the near and the long term. It employs both a scientific and historical approach to accomplish these goals. This volume is intended for practitioners who use antidepressants on a daily basis in their practice as well as for the student and researcher. Each will find that it provides a comprehensive and logical approach to this important group of medications. This book is being published as we mark the end of the first 50 years of the modern antidepressant era.
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Autorenporträt
John P. Feighner, Feighner Research Institute, San Diego, CA, USA / Sheldon H. Preskorn, Univ.of Kansas School of Med.,Wichita, KS, USA / Christina Stanga, Neillsville, WI, USA / Ruth Ross, Ross Editorial, Independence, VA, USA
Inhaltsangabe
1. Basic Principles: Pharmacologic Science.- Biochemical and Physiological Processes in Brain Function and Drug Actions.- General Principles of Pharmacokinetics.- Therapeutic Drug Monitoring of Antidepressants.- 2. Basic Principles: Clinical Science.- Biological Markers of Depression.- Quality of Life and Rating Scales of Depression.- 3. Current Pharmacotherapy of Major Depressive Disorder.- Overview of Currently Available Antidepressants.- Tricyclic Antidepressants.- Monoamine Oxidase Inhibitors.- Selective Serotonin Reuptake Inhibitors.- Other Antidepressants.- Current Role of Herbal Preparations.- 4. Use of Antidepressants in Special Populations.- Children and Adolescents.- Women.- Older Adults.- Bipolar Mood Disorders.- Treatment-Refractory Depression.- Personality Disorders.- 5. Future Directions in the Treatment of Major Depressive Disorder.- New Hypotheses to Guide Future Antidepressant Drug Development.- Promising New Directions in Antidepressant Development.- Role of Pharmacogenetics/Pharmacogenomics in the Development of New Antidepressants.
1. Basic Principles: Pharmacologic Science.- Biochemical and Physiological Processes in Brain Function and Drug Actions.- General Principles of Pharmacokinetics.- Therapeutic Drug Monitoring of Antidepressants.- 2. Basic Principles: Clinical Science.- Biological Markers of Depression.- Quality of Life and Rating Scales of Depression.- 3. Current Pharmacotherapy of Major Depressive Disorder.- Overview of Currently Available Antidepressants.- Tricyclic Antidepressants.- Monoamine Oxidase Inhibitors.- Selective Serotonin Reuptake Inhibitors.- Other Antidepressants.- Current Role of Herbal Preparations.- 4. Use of Antidepressants in Special Populations.- Children and Adolescents.- Women.- Older Adults.- Bipolar Mood Disorders.- Treatment-Refractory Depression.- Personality Disorders.- 5. Future Directions in the Treatment of Major Depressive Disorder.- New Hypotheses to Guide Future Antidepressant Drug Development.- Promising New Directions in Antidepressant Development.- Role of Pharmacogenetics/Pharmacogenomics in the Development of New Antidepressants.
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