Antimicrobial Pharmacodynamics in Theory and Clinical Practice (eBook, PDF)

Redaktion: Nightingale, Charles H.; Murakawa, Takeo; Drusano, George L.; Ambrose, Paul G.

• Format: PDF

Produktbeschreibung

Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging agents currently in development. Written by experienced professionals in the field, this guide uses an abundance of examples to depict methods to apply pharmacodynamic concepts to everyday clinical practice.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 536
• Erscheinungstermin: 15. Juni 2007
• Englisch
• ISBN-13: 9781420017137
• Artikelnr.: 53315754

Autorenporträt

Nightingale, Charles H.; Ambrose, Paul G.; Drusano, George L.; Murakawa, Takeo

Inhaltsangabe

Introduction. Pharmacodynamics of Antimicrobials: General Concepts and
Applications Impact of Pharmacodynamics on Breakpoint Selection for
Susceptibility Testing. Non-Clinical Models of Infection. In Vitro
Antibiotic Pharmacokinetic Models. Animal Models of Infection for the Study
of Antibiotic Pharmacodynamics. The Predictive Value of Laboratory Tests
for Efficacy of Antibiotic Combination Therapy. Antibacterial Agents.
Beta-Lactam Antibiotics. Aminoglycoside Antibiotics. Quinolones.
Glycopeptides. Macrolide, Azalide and Ketolides. Metronidazole, and
Clindamycin. Streptogramins, Oxazolididones. Tetracyclines. Antiviral
Agents. Nucleoside Reverse Transcriptase Inhibitors. Protease Inhibitors.
Hepatitis B and C. Antifungal Agents. Amphotericin. Azoles. Gulcan Synthase
Inhibitors. Antimalarial Agents. Anti-Malarials. Pharmacodynamics in Drug
Development. Human Pharmacodynamics of Anti-Infectives: Determination from
Clinical Trial Data. Pharmacodynamics in Global Bridging Studies.
Toxicodynamics. Pharmacodynamics and Resistance. Antibacterial Resistance.
Application of PK-PD to Clinical and Formulary Decisions. Basic
Pharmacoeconomics. Utilizing Pharmacodynamics and Pharmacoeconomics in
Clinical and Formulary Decision Making.