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This book in the new American Heart Association Clinical Series, explores and explains state-of-the-art use of antiplatelet agents and draws on the expertise of global leaders in antiplatelet therapy. Skillfully organized for fast reference, the book is divided into five parts: * Concepts in Platelet Physiology, Function, and Measurement * Pharmacology of Oral Antiplatelet Agents * Pharmacology of Intravenous Antiplatelet Agents * Clinical Use of Antiplatelet Agents in Cardiovascular Disease * Special Circumstances. Each chapter in the clinical section contains an overview of guidelines, plus…mehr
This book in the new American Heart Association Clinical Series, explores and explains state-of-the-art use of antiplatelet agents and draws on the expertise of global leaders in antiplatelet therapy. Skillfully organized for fast reference, the book is divided into five parts: * Concepts in Platelet Physiology, Function, and Measurement * Pharmacology of Oral Antiplatelet Agents * Pharmacology of Intravenous Antiplatelet Agents * Clinical Use of Antiplatelet Agents in Cardiovascular Disease * Special Circumstances. Each chapter in the clinical section contains an overview of guidelines, plus specifics on medical and interventional uses. Clinical cardiologists, platelet biologists, and a wide range of practicing and prospective clinicians in allied fields will find this text an exceptional source of current information.
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Autorenporträt
Stephen D. Wiviott, MD., Investigator TIMI Study Group, Associate Physician, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Inhaltsangabe
Part I Concepts in Platelet Physiology, Function and Measurement. 1 Platelet physiology and the role of the platelet in ischemic heart disease. Robert F. Storey . 2 Laboratory assessment of platelet function and the effects of antiplatelet agents. Alan D. Michelson, A.L. Frelinger . Part II Pharmacology of Oral Antiplatelet Agents. 3 Cyclooxygenase inhibitors. Nina Chetty Raju, John W. Eikelboom . 4 Aspirin response variability and resistance. Wai-Hong Chen, Daniel I. Simon . 5 P2Y12 inhibitors: Thienopyridines and direct oral inhibitors. Jean-Philippe Collet, Boris Aleil, Christian Gachet, Gilles Montalescot . 6 Thienopyridine response variability and resistance. Udaya S. Tantry, Thomas A. Suarez, Paul A. Gurbel . Part III Pharmacology of Intravenous Antiplatelet Agents. 7 Pharmacology of intravenous glycoprotein IIb/IIIa antagonists. James C. Blankenship, Peter B. Berger . 8 Intravenous P2Y12 inhibitors. Steven P. Dunn, Steven R. Steinhubl . 9 Antiplatelet effects of thrombin inhibitors and fibrinolytic agents. Nicolai Mejevoi, Anjum Tanwir, Marc Cohen . Part IV Clinical Use of Antiplatelet Agents in Cardiovascular Disease. 10 Antiplatelet therapy in acute coronary syndrome with ST elevation. Christian W. Hamm . 11 Antiplatelet therapy in ST-elevation myocardial infarction. Michelle O'Donoghue, Marc S. Sabatine . 12 Antiplatelet therapy in chronic artery disease. Kamran I. Muhammed, Deepak L. Bhatt . 13 Antiplatelet therapy in peripheral arterial disease. Esther S. Kim, Heather L. Gornik . 14 Clinical use of antiplatelet agents in cardiovascular disease: cerebrovascular diseases. Larry B. Goldstein . Part V Special Circumstances. 15 Antiplatelet therapy and coronary bypass surgery: risks and benefits. A. Burdess, N.L. Cruden, K.A. Fox . 16 Management of antiplatelet therapy for non-cardiac surgery. Nisheeth Goel, John F. Canales, James J. Ferguson . 17 Antiplatelet therapy and coronary stents. Alanna Coolong, Laura Mauri
Part I Concepts in Platelet Physiology, Function and Measurement. 1 Platelet physiology and the role of the platelet in ischemic heart disease. Robert F. Storey . 2 Laboratory assessment of platelet function and the effects of antiplatelet agents. Alan D. Michelson, A.L. Frelinger . Part II Pharmacology of Oral Antiplatelet Agents. 3 Cyclooxygenase inhibitors. Nina Chetty Raju, John W. Eikelboom . 4 Aspirin response variability and resistance. Wai-Hong Chen, Daniel I. Simon . 5 P2Y12 inhibitors: Thienopyridines and direct oral inhibitors. Jean-Philippe Collet, Boris Aleil, Christian Gachet, Gilles Montalescot . 6 Thienopyridine response variability and resistance. Udaya S. Tantry, Thomas A. Suarez, Paul A. Gurbel . Part III Pharmacology of Intravenous Antiplatelet Agents. 7 Pharmacology of intravenous glycoprotein IIb/IIIa antagonists. James C. Blankenship, Peter B. Berger . 8 Intravenous P2Y12 inhibitors. Steven P. Dunn, Steven R. Steinhubl . 9 Antiplatelet effects of thrombin inhibitors and fibrinolytic agents. Nicolai Mejevoi, Anjum Tanwir, Marc Cohen . Part IV Clinical Use of Antiplatelet Agents in Cardiovascular Disease. 10 Antiplatelet therapy in acute coronary syndrome with ST elevation. Christian W. Hamm . 11 Antiplatelet therapy in ST-elevation myocardial infarction. Michelle O'Donoghue, Marc S. Sabatine . 12 Antiplatelet therapy in chronic artery disease. Kamran I. Muhammed, Deepak L. Bhatt . 13 Antiplatelet therapy in peripheral arterial disease. Esther S. Kim, Heather L. Gornik . 14 Clinical use of antiplatelet agents in cardiovascular disease: cerebrovascular diseases. Larry B. Goldstein . Part V Special Circumstances. 15 Antiplatelet therapy and coronary bypass surgery: risks and benefits. A. Burdess, N.L. Cruden, K.A. Fox . 16 Management of antiplatelet therapy for non-cardiac surgery. Nisheeth Goel, John F. Canales, James J. Ferguson . 17 Antiplatelet therapy and coronary stents. Alanna Coolong, Laura Mauri
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