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Microarrays play an increasingly significant role in drug discovery. Updated and revised to reflect recent progress in the field, the second edition of this volume discusses omics-driven applications, the commercialization of the microarray platform, and solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays. It examines different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented. It also explores the development of the gene expression microarray and…mehr

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Produktbeschreibung
Microarrays play an increasingly significant role in drug discovery. Updated and revised to reflect recent progress in the field, the second edition of this volume discusses omics-driven applications, the commercialization of the microarray platform, and solid-supports (substrates) and surface chemistries currently used in the creation of nucleic acid and protein microarrays. It examines different approaches to producing microarrays that achieve spot equality with the same number of molecules properly oriented. It also explores the development of the gene expression microarray and representative applications and the development of protein microarray technology.

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Autorenporträt
Robert S. Matson is president and co-founder of QuantiScientifics, LLC. The company is involved in the commercialization of multiplexed assays for life science, clinical research, and in vitro diagnostics. Previously, Matson was involved in the research and development of microarray technologies, detection chemistries, as well as point-of-care devices for more than 17 years while at Beckman Coulter, Inc. He participated in the National Institute of Standards and Technology's (NIST) Advanced Technology Program sponsored Genosensor Consortium and collaborated with Sir Edwin Southern on the development of an in situ oligonucleotide array synthesis platform for the corporation. Other work included development of the A2 MicroArray System, a microplate-based array platform for multiplexed micro-ELISA, which QuantiScientifics recently licensed for commercialization.