Organized into nine chapters, this volume starts with an overview of the structure-activity relationship of ß-endorphin (ß-EP) by synthetic approach. This text then explores the proteinases involved in the generation of opioid peptides, including ß-EP from ß-lipotropin (ß-LPH). Other chapters review the biosynthesis of ß-EP and consider in detail the opiate receptor. This book discusses as well the anatomy of ß-EP-containing structures in pituitary and brain. The final chapter presents a discussion on the historical aspects of opiate-peptide discoveries, particularly in the field of narcotic antagonists.
This book is a valuable resource for chemists, biologists, endocrinologists, physicians, and neurobiologists.
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