Bacterial Cell-to-Cell Communication (eBook, PDF)

Role in Virulence and Pathogenesis
Redaktion: Demuth, Donald R.

• Format: PDF

Produktbeschreibung

Many bacterial diseases are caused by organisms growing together as communities or biofilms. These microorganisms have the capacity to coordinately regulate specific sets of genes by sensing and communicating amongst themselves utilizing a variety of signals. This book examines the mechanisms of quorum sensing and cell-to-cell communication in bacteria and the roles that these processes play in regulating virulence, bacterial interactions with host tissues, and microbial development. Recent studies suggest that microbial cell-to-cell communication plays an important role in the pathogenesis of a variety of disease processes. Furthermore, some bacterial signal molecules may possess immunomodulatory activity. Thus, understanding the mechanisms and outcomes of bacterial cell-to-cell communication has important implications for appreciating host-pathogen interactions and ultimately may provide new targets for antimicrobial therapies that block or interfere with these communication networks.

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Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 23. Februar 2006
• Englisch
• ISBN-13: 9780511133657
• Artikelnr.: 38198958

Autorenporträt

Donald R. Demuth is Professor in the Department of Periodontics, Endodontics and Dental Hygiene at the University of Louisville School of Dentistry.
Richard Lamont is Professor of Oral Biology at the University of Florida.

Inhaltsangabe

Introduction Donald R. Demuth and Richard Lamont; 1. Quorum sensing and
regulation of P. aeruginosa infections Victoria E. Wagner and Barbara
Iglewski; 2. The Pseudomonas aeruginosa quinolone signal Everett Pesci; 3.
Quorum sensing mediated regulation of plant/bacteria interactions and A.
tumafaciens virulence Catharine C. White and Stephen C. Winans; 4. Jamming
bacterial communications: new strategies to combat bacterial infections and
the development of biofilms Michael Givskov and Morton Hentzer; 5. Quorum
sensing-mediated regulation of biofilm growth and virulence of Vibrio
cholerae Jun Zhu and John. J. Mekalanos; 6. LuxS in cellular metabolism and
cell-cell signaling Kangmin Duan and Michael Surette; 7. LuxS dependent
regulation of E. coli virulence Marcie B. Clarke and Vanessa Sperandio; 8.
Quorum sensing and cell-to-cell communication in the dental biofilm Donald
R. Demuth and Richard Lamont; 9. Quorum sensing-dependent regulation of
staphylococcal virulence and biofilm development Jeremy Yarwood; 10. Cell
density dependent regulation of streptococcal competence M. Dilani
Senadheera, Celine Levesque and D. Cvitkovitch; 11. Signaling by a cell
surface-associated signal during fruiting body morphogenesis in Myxococcus
xanthus Lotte Søgaard-Andersen.