This book is organized into six parts encompassing 79 chapters. Considerable chapters tackle the origin and classification of tumors; normal clones of T and B cells; differentiation of T and B cell tumors; regulation of tumor growth and tumor therapy. Each topic is discussed based on the results obtained in human and animal models in the laboratory. Other chapters explore lymphoid neoplasms and the enormous progress made in applying the technologies of monoclonal antibodies, cell cloning/long-term culture, and genetic analysis to questions concerning lymphoid tumors. The remaining chapters consider the malignant lymphoid cell as a model for growth and regulation, and the insights emerging from these studies, which are being applied to the development of new modalities for therapy and diagnosis.
This book will be of value to scientists and clinicians who are interested in the mechanism of B and T cell tumorigenesis.
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