Bioactive Compounds from Natural Sources (eBook, PDF)

Natural Products as Lead Compounds in Drug Discovery
Redaktion: Tringali, Corrado

• Format: PDF

Produktbeschreibung

This book focuses on the modern approach to the isolation of biologically active natural products and provides numerous examples of the isolation and characterization of secondary metabolites. It emphasizes the synthetic or semi-synthetic analogues of natural products, relevant to those working on biomedical applications of natural products. It includes chapters on general methods together with more specific chapters discussing the main topics in the field, including important families or properties of bioactive natural products, synthesis of analogues, biological evaluation of both natural and synthetic products, and structure-activity relationship studies.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 648
• Erscheinungstermin: 27. September 2011
• Englisch
• ISBN-13: 9781439870662
• Artikelnr.: 57534044

Autorenporträt

Professor Corrado Tringali obtained his BA in chemistry at the University of Catania, Italy, in 1973. From 1977 to 1985 he was an assistant professor, teaching courses in organic chemistry and physical methods in organic chemistry. In November 1985 he became an associate professor (organic chemistry), and since November 2001 he has been a full professor (teaching courses in organic chemistry, natural products chemistry, and physical methods in organic chemistry). At present, he is coordinator of the international Doctorate of Research in Chemical Science program at the University of Catania (Cycles XXII -XIV).

Inhaltsangabe

Strategies and Methods for a Sustainable Search for Bioactive Compounds.
Discovery of Potential Anticancer Agents from Aquatic Cyanobacteria,
Filamentous Fungi, and Tropical Plants. Metabolic Engineering of Natural
Product Biosynthesis. Computational Approaches for the Discovery of Natural
Lead Structures. Recent Advances in the Application of Electronic Circular
Dichroism for Studies of Bioactive Natural Products. Natural Products as
Treatments for and Leads to Active Compounds in Viral Diseases. Natural
Products as Inhibitors of Hypoxia-Inducible Factor-1 (HIF-1). From
Antitumor or Wound Healing Actions of Natural Products through
Angiogenesis. From Natural Polyphenols to Synthetic Antitumor Agents.
Resveratrol against Major Pathologies: From Diet Prevention to Possible
Alternative Chemotherapies with New Structural Analogues. Drug Discovery
from Natural Substances-A Case Study: Camptothecins. Plant Compounds and
Derivatives as Inhibitors of Cancer Cell Multidrug Resistance. Recent
Advances in the Search of Novel Calmodulin Inhibitors from Selected Mexican
Plants and Fungi. Neuroprotective Effects of Natural Products from
Traditional Chinese Herbs. Drugs for the Neglected Disease Malaria based on
Natural Products. Endophytic Microorganisms as a Source of Bioactive
Compounds. Biologically Active Natural Products from Australian Marine
Organisms.