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Integrates biochemical, molecular, and cellular health and disease processes into one essential text! Biochemistry, Cell and Molecular Biology, and Genetics: An Integrated Textbook by Zeynep Gromley and Adam Gromley is the first to cover molecular biology, cell biology, biochemistry (metabolism), and genetics in one comprehensive yet concise resource. Throughout the book, these topics are linked to other basic medical sciences, such as pharmacology, physiology, pathology, immunology, microbiology, and histology, for a truly integrated approach. Key Highlights Easy-to-read text…mehr
Integrates biochemical, molecular, and cellular health and disease processes into one essential text!
Biochemistry, Cell and Molecular Biology, and Genetics: An Integrated Textbook by Zeynep Gromley and Adam Gromley is the first to cover molecular biology, cell biology, biochemistry (metabolism), and genetics in one comprehensive yet concise resource. Throughout the book, these topics are linked to other basic medical sciences, such as pharmacology, physiology, pathology, immunology, microbiology, and histology, for a truly integrated approach.
Key Highlights
Easy-to-read text enhances understanding of underlying molecular mechanisms of disease
Nearly 500 illustrations and tables help reinforce chapter learning objectives
Textboxes throughout make connections with other preclinical disciplines
End of unit high-order clinical vignette questions with succinct explanations help integrate basic science topics with clinical medicine
This textbook provides a robust review for medical students preparing for courses as well as exams. Dental, pharmacy, physician's assistant, nursing, and graduate students in pre-professional/bridge programs will also find this a beneficial learning tool.
This book includes complimentary access to a digital copy on https://medone.thieme.com.
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Inhaltsangabe
Part I 1. Anatomy of the Cell and Organelles 2. DNA Replication, Gene Mutations, and Repair 3. Transcription and Regulation of Transcription 4. Translation and Regulation of Translation Part II 5. Cytoskeleton 6. Protein Sorting, Modifications, and Intracellular Traffic 7. Membrane Transport 8. Extracellular Matrix 9. Cell Adhesion and Membrane Junctions 10. Signal Transduction 11. Cell Cycle and Control of the Cell Cycle 12. Stem Cells and Hematopoiesis 13. Cell Injury, Apoptosis, and Necrosis 14. Hallmarks of Cancer and Cancer Biology 15. Molecular Principles of Cancer Treatments and Therapies Part III 16. Enzymes and Enzyme Kinetics 17. Regulation of Enzyme Activity 18. Structure and Function of Proteins 19. Molecular and Biological Techniques 20. Plasma Proteins and the Diagnostic Use of Enzymes Part IV 21. Digestion and Absorption of Carbohydrates 22. Glycolysis 23. Metabolism of Fructose, Galactose and the Pentose Phosphate Pathway (HMP Shunt) 24. Glycogen Metabolism and Regulation 25. Gluconeogenesis 26. Pyruvate Dehydrogenase and Tricarboxylic Acid (TCA) Cycle 27. Electron Transport Chain (ETC) and Oxidative Phosphorylation 28. Oxygen Toxicity and Antioxidants 29. Oxidation of Fatty Acids and Ketogenesis 30. Acid Base Chemistry and Acid Base Disorders 31. Glucose Homeostasis and Maintenance of Blood Glucose Concentrations Part V 32. Digestion and Absorption of Proteins 33. Nitrogen Metabolism 34. Amino Acid Metabolism 35. Amino Acid Derivatives 36. Porphyrin Heme Metabolism and Iron Homeostasis 37. Nucleotide Metabolism 38. Vitamins in One-Carbon Metabolism Part VI 39. Digestion and Absorption of Lipids 40. Synthesis of Fatty Acids and Triacylglycerols 41. Metabolism of Membrane Lipids and Lipid Derivatives 42. Cholesterol Metabolism 43. Blood Lipoproteins 44. Steroid Hormones and Vitamin D 45. Nutrition and Metabolism 46. Vitamins and Minerals Part VII 47. DNA Packaging and Meiosis 48. Cytogenetics: Chromosomal Basis of Human Diseases 49. Single Gene Disorders: Autosomal Dominant and Recessive Inheritance 50. Sex-Linked and Non-Traditional Modes of Inheritance 51. Population Genetics 52. Genomic Imprinting and Epigenetics 53. Gene Interactions and Multifactorial Inheritance 54. Personalized Medicine 55. Developmental Genetics 56. Cancer Genetics
Part I 1. Anatomy of the Cell and Organelles 2. DNA Replication, Gene Mutations, and Repair 3. Transcription and Regulation of Transcription 4. Translation and Regulation of Translation Part II 5. Cytoskeleton 6. Protein Sorting, Modifications, and Intracellular Traffic 7. Membrane Transport 8. Extracellular Matrix 9. Cell Adhesion and Membrane Junctions 10. Signal Transduction 11. Cell Cycle and Control of the Cell Cycle 12. Stem Cells and Hematopoiesis 13. Cell Injury, Apoptosis, and Necrosis 14. Hallmarks of Cancer and Cancer Biology 15. Molecular Principles of Cancer Treatments and Therapies Part III 16. Enzymes and Enzyme Kinetics 17. Regulation of Enzyme Activity 18. Structure and Function of Proteins 19. Molecular and Biological Techniques 20. Plasma Proteins and the Diagnostic Use of Enzymes Part IV 21. Digestion and Absorption of Carbohydrates 22. Glycolysis 23. Metabolism of Fructose, Galactose and the Pentose Phosphate Pathway (HMP Shunt) 24. Glycogen Metabolism and Regulation 25. Gluconeogenesis 26. Pyruvate Dehydrogenase and Tricarboxylic Acid (TCA) Cycle 27. Electron Transport Chain (ETC) and Oxidative Phosphorylation 28. Oxygen Toxicity and Antioxidants 29. Oxidation of Fatty Acids and Ketogenesis 30. Acid Base Chemistry and Acid Base Disorders 31. Glucose Homeostasis and Maintenance of Blood Glucose Concentrations Part V 32. Digestion and Absorption of Proteins 33. Nitrogen Metabolism 34. Amino Acid Metabolism 35. Amino Acid Derivatives 36. Porphyrin Heme Metabolism and Iron Homeostasis 37. Nucleotide Metabolism 38. Vitamins in One-Carbon Metabolism Part VI 39. Digestion and Absorption of Lipids 40. Synthesis of Fatty Acids and Triacylglycerols 41. Metabolism of Membrane Lipids and Lipid Derivatives 42. Cholesterol Metabolism 43. Blood Lipoproteins 44. Steroid Hormones and Vitamin D 45. Nutrition and Metabolism 46. Vitamins and Minerals Part VII 47. DNA Packaging and Meiosis 48. Cytogenetics: Chromosomal Basis of Human Diseases 49. Single Gene Disorders: Autosomal Dominant and Recessive Inheritance 50. Sex-Linked and Non-Traditional Modes of Inheritance 51. Population Genetics 52. Genomic Imprinting and Epigenetics 53. Gene Interactions and Multifactorial Inheritance 54. Personalized Medicine 55. Developmental Genetics 56. Cancer Genetics
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