Biogenic Amine Receptors (eBook, PDF)

Redaktion: Iversen, Leslie

• Format: PDF

Produktbeschreibung

Zur Zeit liegt uns keine Inhaltsangabe vor.

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Produktdetails

• Verlag: Springer New York
• Seitenzahl: 307
• Erscheinungstermin: 29. November 2012
• Englisch
• ISBN-13: 9781468485141
• Artikelnr.: 44059181

Inhaltsangabe

1 Amine Receptors in CNS. I. Norepinephrine.- 1. Introduction.- 2. Localizing Norepinephrine-Containing Synapses.- 3. Effects of Norepinephrine on Central Neurons.- 4. Action of Norepinephrine on Defined Postsynaptic Neurons.- 5. The Noradrenergic Projection to Rat Hippocampal Pyramidal Cells and Other Brain Stem Areas.- 6. Cyclic 3?,5?-Adenosine Monophosphate as a Mediator of Norepinephrine Action in the Central Nervous System.- 7. Conclusions.- 8. References.- 2 Amine Receptors in CNS. II. Dopamine.- 1. Introduction.- 2. Localization and Function of Dopamine.- 3. Synthesis and Degradation of Striatal Dopamine.- 4. Stimulus-Evoked Release of Dopamine in Striatum.- 5. Dopamine Receptor Activation: Effects of Dopamine on Striatal Neurons.- 6. Pharmacological Characterization of Presumed Dopaminergic Neurons.- 7. Presynaptic vs. Postsynaptic Dopamine Receptors.- 8. Behavioral Studies.- 9. Structural Conformations.- 10. Dopamine Receptor: Adenylate Cyclase.- 11. Conclusion.- 12. References.- 3 Amine Receptors in CNS. III. 5-Hydroxytryptamine in Brain.- 1. Introduction.- 2. Experimental Studies on 5-HT Receptors.- 3. Conclusions.- 4. References.- 4 Acetylcholine Receptors in Vertebrate CNS.- 1. Introduction.- 2. In Vivo Effects of ACh and Agonists on CNS.- 3. In Vitro Effects of ACh and Agonists on CNS.- 4. Significance of ACh Receptors.- 5. Evidence for Central Cholinergic Neurotransmission and Its Functional Significance.- 6. References.- 5 Receptor Feedback and Dopamine Turnover in CNS.- 1. Introduction.- 2. Dopamine as a Transmitter Substance in CNS.- 3. T ransmitter Metabolism in Brain Dopamine Neurons.- 4. Effect of Dopamine Receptor Blocking Drugs on Transmitter Turnover.- 5. Effect of Dopamine Receptor Stimulating Drugs on Transmitter Turnover.- 6. RelationBetween Drug Effects on Dopamine Turnover Regulation in Vivo and Dopamine-Stimulated Adenylate Cyclase Activity in Vitro.- 7. Evidence for Receptor-Mediated Control of Brain Dopamine Turnover in Man.- 8. References.- 6 Basic Mechanisms and Local Feedback Control of Secretion of Adrenergic and Cholinergic Neurotransmitters.- 1. Introduction.- 2. Secretion of Adrenergic and Cholinergic Neurotransmitters.- 3. Local Feedback Control of Secretion of Adrenergic and Cholinergic Neurotransmitters.- 4. References.- 7 The Cholinergic Receptor Protein from Fish Electric Organ.- 1. Introduction.- 2. A Model for the Electrogenic Action of Acetylcholine.- 3. Anatomy of the Electric Organs and of the Electroplaques.- 4. The Electric Discharge and the Electrophysiology of the Electroplaques.- 5. Pharmacology of the Isolated Electroplaque from Electrophorus.- 6. Localization of the Cholinergic Receptor Site in Electrophorus Electroplaque.- 7. Subcellular Fractionation of the Electric Organ.- 8. Permeability Response of Isolated Microsacs to Cholinergic Agonists.- 9. Characterization of the Cholinergic Receptor Site on Excitable Microsacs.- 10. Solubilization and Purification of the Cholinergic Receptor Protein.- 11. Chemical Properties of the Purified Receptor Protein.- 12. Physical Properties of the Cholinergic Receptor Protein.- 13. Binding Properties of the Purified Protein.- 14. Immunological Characterization of the Cholinergic Receptor Protein from Electrophorus.- 15. Conformational Transitions of the Receptor Protein Associated with Its Physiological Function.- 16. Turnover Number of the Cholinergic Ionophore.- 17. Reconstruction of a Chemically Excitable Membrane.- 18. Conclusion.- 19. References.