Robert Arking

Biology of Longevity and Aging (eBook, PDF)

Observations and Principles

• Format: PDF

Produktbeschreibung

The latest edition of Robert Arking's seminal text on the biology of aging takes on an extended title, since the field of gerontology has advanced to a point at which it is possible to separate the topic into two implicit subsets, longevity and aging. This multi-faceted description of the biology of aging guides the reader through increasingly interesting answers to seven fundamental questions: What is aging? Why do we age? What mechanisms support extended longevity? What determines the onset of senescence? What is the mechanistic basis of senescence? Why do humans live so long? And lastly, what pro-longevity societal interventions are needed? Inevitably, humans will age but there is no reason why we must suffer from age-related diseases. Aging and longevity are dependent on both genes and social environment. Our biology does not forbid the modulation of aging. What we really want to know is not so much about the biology of aging - which is basically a degenerative process - but rather about biological processes underlying the long term maintenance of our health. New chapters incorporate the latest developments in the field of gerontology. Research done since the previous edition was published has given us insight into how we may stay healthier longer.

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Produktdetails

• Verlag: Oxford University Press
• Seitenzahl: 672
• Erscheinungstermin: 4. Dezember 2018
• Englisch
• ISBN-13: 9780199387977
• Artikelnr.: 54660530

Autorenporträt

Robert Arking is Professor of Biological Sciences at Wayne State University. His research delves into the mechanisms underlying both senescence and extended longevity in Drosophila. He has published widely on these topics, and is a Fellow of both the Gerontology Society of America and the American Aging Association. He was a Fulbright Fellow at the University of Salzburg, Austria; and was twice invited to serve as an "Expert Visiting Professor" at Pusan University in South Korea.

Inhaltsangabe

* Part I: What is Aging?
* Chapter 1. Perspectives on Aging.
* Chapter 2. Measuring Age-related Changes in Populations
* Chapter 3. Measuring Age-related Changes in Individuals
* Part 2: Why Do We Age?
* Chapter 4 Evolutionary and Comparative Aspects of Longevity and
Senescence
* Part 3: What Mechanisms Modulate Our Longevity?
* Chapter 5 Interventions That Modify Longevity
* Chapter 6 Genetic and Social Aspects Affecting Human Longevity
* Chapter 7 Genetic Determinants of Longevity in Animal and Human
Models
* Part 4: What Mechanisms Modulate Our Aging and Senescence?
* Chapter 8 What Mechanisms Underlie the Transition from Health to
Senescence
* Chapter 9 Human Senescent Phenotypes
* Chapter 10 Stochastic Mechanisms of Senescence
* Chapter 11 Systemic Mechanisms of Senescence
* Chapter 12 Senescence as a Breakdown of Intracellular Regulatory
Processes.
* Chapter 13 Senescence as a Breakdown of Intercellular Regulatory
Processes
* Part 5: An Integrated View of Longevity and Aging Mechanisms
* Chapter 14 Biological Theories of Senescence and the Evolution of
Extended Longevity
* Chapter 15 Aging -related Research and It's Impact on Society.
* References
* Index