Biomimetic organic synthesis transposes the efficiency of nature's chemistry into the laboratory. Natural products (also known as secondary metabolites) are among the best examples of how nature can assemble atoms into highly complex structures. Therefore, biomimetic total syntheses of natural products (in which biosynthesis considerations guide the synthetic strategy) constitute the major focus of this book, with emphasis on the developments of the last 10 to 15 years. Important key definitions and general concepts are described in a tutorial way and additional chapters develop some frontier fields that may benefit to or from biomimetic synthesis. The book has been organized according to the main biosynthetic pathways: Volume 1: alkaloids derived from ornithine, arginine, lysine, tyrosine, tryptophane; manzamine alkaloids; pyrrole-2-aminoimidazole and guanidinium alkaloids; peptide alkaloids; alkaloids with a non-amino acid origin. Volume 2: Terpenoids and polyprenylated compounds; polyketides: aromatic, non aromatic, polyethers, electrocyclization pathways, lignans, resveratrol-derived and tannin polyphenols; frontiers in biomimetic organic synthesis: Diels-Alderases, transfer hydrogenations, life's single chirality, artifacts in natural product chemistry. This two-volume book is made up of 24 contributions from 33 authors. Graduate students, teachers and researchers in the fields of organic and bio-organic chemistry, who enjoy total syntheses, synthetic strategies and biosyntheses, will be the happy users of this book.
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