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The second edition of this popular title presents the most exciting approaches for engineering biologically active nanostructures. A particular stress is placed on purely artificial assemblies created to deliver a specialist biological function or mechanism. Such synthetic designs emulate naturally occurring nanoscale forms of viruses and matrices, pores and channels, but their functional properties are not necessarily those normally observed in Nature. Therefore, it is said that the forms may be same, but functions they adopt are new. The volume is structured around prominent topics of…mehr
The second edition of this popular title presents the most exciting approaches for engineering biologically active nanostructures. A particular stress is placed on purely artificial assemblies created to deliver a specialist biological function or mechanism. Such synthetic designs emulate naturally occurring nanoscale forms of viruses and matrices, pores and channels, but their functional properties are not necessarily those normally observed in Nature. Therefore, it is said that the forms may be same, but functions they adopt are new. The volume is structured around prominent topics of biological nanodesign with an integrated perspective of the impact nanoscale engineering has on the emerging field of synthetic biology. Nanostructured materials assembled from DNA, proteins and lipids and advances they offer for medicine are discussed. Written by a world recognised expert, this book provides an authorative guide to those working in design and development of nanomaterial research in industry and academia, from postgraduate researchers upwards.
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Autorenporträt
Max Ryadnov leads Biometrology research area at NPL. He is also a visiting Professor at King's College London and a Fellow of the Royal Society of Chemistry and the Royal Society of Biology. Max obtained his MSc in Biochemistry (summa cum laude) from the Russian Academy of Sciences and PhD in Chemistry from Moscow State University. Following his academic tenures at Bristol (URF) and Leicester (Lecturer), he joined NPL as a Principal Research Scientist in 2010. Over the last 10 years, his contributions to physical and life sciences have been recognised by a NESTA Crucible Innovation Award, a SUPA lectureship in Chemical Physics with the University of Edinburgh and Fellowships in the Royal Society of Chemistry and the Royal Society of Biology. He has authored over 100 peer-reviewed publications (incl. primary reports in Angew Chem, JACS, Nature Mater, Nature Commun, PNAS), numerous book chapters, two books, several international patents, and is a co-editor of two RSC book series - Amino Acids, Peptides and Proteins and Synthetic Biology.
Inhaltsangabe
1. INTRODUCTORY NOTES. Inspiring hierarchical.- Encoding instructive.- Starting lowest.- Picturing biological. 2. RE-CYCLING HEREDITARY. Coding dual.- Deoxyribonucleic.- Building up in two.- Keeping in shape.- Priming topological.- Re-sequencing basic.- Choosing the fittest.- Evolving diverse.- Primary motifs.- Gluing universal.- Alienating axial.- Fixing spatial.- Hinting geometric: secondary motifs.- Crossing double.- Reporting visible.- Translating symmetrical.- Extending cohesive.- Sharing mutual.- Multiplying traversal.- Tiling square.- Scaffolding algorithmic.- Pursuing autonomous.- Lengthening to shorten.- Gathering to limit.- Assigning arbitrary.- Synchronizing local.- Prescribing general.- Adding up to third.- Wrapping to shut.- Framing to classify.- Outlook.- References. 3. RE-CAGING WITHIN. Enclosing to deliver.- Transporting foreign.- Fitting flat and straight.- Spiraling along.- Packing out and in.- Spooling around.- Tunneling through.- Escaping walled.- Capturing on and off.- Storing exchangeable.- Reacting nano.- Clustering spherical.- Contriving consistent.- Scaling hosting.- Following linear.- Channeling inner.- Converting outer.- Repairing from inside.- Uninviting levy.- Necessitating exterior.- Antagonizing dressing.- Buffering masking.- Renting occasional.- Phasing wet.- Facing concentric.- Encircling between.- Singling out unique.- Sharing the balance.- Driving symmetrical.- Sealing annular.- Outlook.- References. 4. RE-ASSEMBLING MULTIPLE. Keeping all in touch.- Unraveling the essential.- Winding three in one.- Aligning stagger.- Tapering polar.- Branching and stretching.- Replicating apparent.- Scrapping refusal.- Tempting compatible.- Likening synthetic.- Recovering intelligent.- Restoring available.- Prompting longitudinal.- Invoking granted.- Reposing modular.- Displacing coil.- Settling lateral.- Bundling exclusive.- Permitting distinctive.- Inviting captive.- Clearing limiting.- Equilibrating transitional.- Extracting minimal.- Gambling beyond.- Guiding proliferative.- Feeding proximate.- Rooting renewal.- Accepting inescapable.- Patterning positional.- Relating interfacial.- Grafting integral.- Outlook.- References. 5. CONCLUDING REMARKS. Learning fluent.- Parsing semantic.- Drawing pragmatic. 6. REVEALING CONTRIBUTORY.
