Sylvia Wassertheil-Smoller

Biostatistics and Epidemiology (eBook, PDF)

A Primer for Health and Biomedical Professionals

• Format: PDF

Produktbeschreibung

Since the publication of the first edition, BIOSTATISTICS AND EPIDEMIOLOGY has continued to garner loyal readers from across speciality areas in the biomedical community. BIOSTATISTICS AND EPIDEMIOLOGY provides clear, concise explanations of the underlying principles of statistics and epidemiology, as well as practical guidelines of "how to do it" and "how to interpret it."

Through its several editions, BIOSTATISTICS AND EPIDEMIOLOGY has continued to adapt to evolving areas of research in epidemiology and statistics, while maintaining the original objective of being non-threatening, understandable and accessible to those with limited or no background in mathematics. Two new areas are covered in the third edition: genetic epidemiology and research ethics.

With the sequencing of the human genome, there has been a flowering of research into the genetic basis of health and disease, and especially the interactions between genes and environmental exposures. The medical literature in genetic epidemiology is vastly expanding and some knowledge of the epidemiological designs and an acquaintance with the statistical methods used in such research is necessary in order to be able to appreciate new findings. Thus this edition includes a new chapter on genetic epidemiology as well as an Appendix describing the basics necessary for an understanding of genetic research. Such material is not usually found in first level epidemiology or statistics books, but it is presented here in a basic, and hopefully easily comprehensible way, for those unfamiliar with the field. The second new chapter is on research ethics, also not usually covered in basic textbooks, but critically important in all human research . New material has also been added to several existing chapters.

I hope this book will be useful to diverse groups of people in the health field, as well as to those in related areas. The material is intended for (1) physicians doing clinical research as well as for those doing basic research; (2) for students-medical, college, and graduate; (3) for research staff in various capacities; and (4) for anyone interested in the logic and methodology of biostatistics and epidemiology. The principles and methods described here are applicable to various substantive areas, including medicine, public health, psychology, and education. (from the Preface)

Whether used as a brief textbook in a classroom or as a refresher for more advanced readers, BIOSTATISTICS AND EPIDEMIOLOGY has become a well-thumbed and battered resource in many a classroom, department library and lab. With the explosion of biomedical research and publishing in the past few years, understanding the statistical validity of the results of both basic research and clinical trials has never been more important. This new third edition of BIOSTATISTICS AND EPIDEMIOLOGY serves as the roadmap to understanding these complex and important topics.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 244
• Erscheinungstermin: 10. Mai 2006
• Englisch
• ISBN-13: 9780387218298
• Artikelnr.: 43999892

Autorenporträt

Sylvia Wassertheil-Smoller, PhD, is professor of epidemiology in the Department of Epidemiology and Population Health at the Albert Einstein College of Medicine and is the Dorothy and William Manealoff Foundation and Molly Rosen Chair in Social Medicine, Emerita. In addition to her teaching, her research spans both cardiovascular disease and cancer epidemiology. She has been a leader in landmark clinical trials in the prevention of heart disease and stroke and in major national and international collaborative prospective studies that have informed guidelines for medical practice. She has won awards for mentoring students and junior faculty, as well as the Einstein Spirit of Achievement Award. She lives in New York. Jordan Smoller, MD, ScD, is professor of psychiatry at Harvard Medical School and professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health in Boston. He is director of the Psychiatric and Neurodevelopmental Genetics Unit in the Massachusetts General Hospital (MGH) Center for Genomic Medicine,  director of the Center for Precision Psychiatry at MGH, and an Associate Member of the Broad Institute of MIT and Harvard. The focus of Dr. Smoller's research is understanding the genetic and environmental determinants of psychiatric disorders across the lifespan and using big data to advance precision mental health including improved methods to reduce risk and enhance resilience.  He is the recipient of numerous research awards, an author of more than 500 scientific articles, book chapters and reviews, and author of the book The Other Side of Normal (HarperCollins/William Morrow, 2012). He lives with his family in Boston.

Inhaltsangabe

1. The Scientific Method.- 2. A Little Bit of Probability.- 3. Mostly About Statistics.- 4. Mostly About Epidemiology.- 5. Mostly About Screening.- 6. Mostly About Clinical Trials.- 7. Mostly About Quality of Life.- 8. Mostly About Genetic Epidemiology.- 9. Risk Prediction and Risk Classification.- 10. Research Ethics and Statistics.- Postscript.- Appendix A.- Appendix B.- Appendix C.- Appendix D.- Appendix E.- Appendix F.- Appendix G. References.- Suggested Readings.- Index.

Rezensionen

"The intended audience includes physicians doing clinical or basic research; medical students and college or graduate level students; researchers in biomedical sciences and epidemiology as well as those interested in genetic epidemiology; and anyone interested in the logic and methodology of biostatistics, epidemiology, and genetic epidemiology. ... This book presents the basics on biostatistics and epidemiology in biomedical science and incorporates new information on genetic epidemiology and risk prediction based on new biomarkers." (Hemang B. Panchal, Doody's Book Reviews, June, 2015)