Rolf D. Schmid, Claudia Schmidt-Dannert

Biotechnology (eBook, PDF)

An Illustrated Primer
Illustrator: Hammelehle, Ruth

• Format: PDF

Produktbeschreibung

This sequal to the "Pocket Guide to Biotechnology and Genetic Engineering", now in a large format, is ideal for exam preparations as well as serving as a handy reference for professionals, offering a concise and readily understandable overview of all important topics in modern biotechnology and genetic engineering. The content has been completely updated and restructured to reflect recent trends and developments and to follow the teaching curricula of most academic courses. New entries include glycobiology, algae, epigenetics, pre- and probiotics as well as C-sources and synthetic biology. The textbook still contains entries on the key topics in fermentation, bioprocess engineering and enzyme technology, along with industrial applications of biotechnology, focusing on the fields of food and medicine. The basic terms of microbiology, biochemistry, genetic engineering and cell biology are explained via an attractive layout including full color plates and the corresponding explanatory text. The whole is rounded off by a section on agricultural and environmental topics, as well as safety and ethical aspects. The result is the number-one primer in biotechnology.

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Produktdetails

• Verlag: Wiley-VCH
• Erscheinungstermin: 21. März 2016
• Englisch
• ISBN-13: 9783527677566
• Artikelnr.: 44849798

Autorenporträt

Rolf Schmid studied chemistry, biochemistry and microbiology in Munich and Freiburg (Germany). After postdoctoral training in Gif-sur-Yvette (France) and Austin (USA), he joined Henkel KGaA in Dusseldorf (Germany) where he worked for 15 years, eventually as Director R&D Biotechnology. In 1987, he was invited to direct the Institute for Enzyme Technology at Braunschweig Technical University and the Division of Enzyme Technology and Chemistry of Natural Products at the 'Gesellschaft für biotechnologische Forschung' (GBF) in Braunschweig (Germany). From 1993 to 2009, he was Director of the Institute for Enzyme Technology at Stuttgart University (Germany). After having obtained an MBA diploma from the University of Reutlingen in 2007, he founded the consulting agency www.bio4business.eu in Stuttgart, followed in 2015 by the Steinbeis Consulting Agency www.asia-tech.eu. Dr. Claudia Schmidt-Dannert is Distinguished McKnight Professor in the Department of Biochemistry, Molecular Biology and Biophysics, at the University of Minnesota (USA). She studied Biology and Biochemistry at the Carolo Wilhelmina University Braunschweig (Germany), where she received her Ph.D. in Biochemistry in 1994. Schmidt-Dannert held a Postdoc position in Molecular Biotechnology at the University of Stuttgart (Germany) and became Professor at the University of Minnesota in 2010. Her research focuses on exploring and utilizing the metabolic machineries of plants and microorganisms to enable the discovery and synthesis of valuable microbial or plant-derived compounds in engineered microbial cells.

Inhaltsangabe

INTRODUCTION
Early developments
Biotechnology today
MICROBIOLOGICAL FUNDAMENTALS
Viruses
Bakteriophags
Microorganisms
Bacteria
Bacteria: charakterization
Fungi
Yeasts
Microorganisms: isolation, stem maintenance, safety
Stem maintenance of microorganisms
FUNDAMENTALS OF BIOPROCESS ENGINEERING
Culture
growth kinetics and product formation
fed-batch and continuous fermentations
Fermentation technique
Fermentation technique: upscaling
Cultivation of animal cells
Cultivation of animal cells: technical concepts
Enzyme and cell reactors
Downstream processing of bioproducts
Downstream processing of bioproducts: chromatography
Industrial processes
MOLECULAR GENETIC METHODS
DNA: structure
DNA: Function
Gene technology: general working steps
Preparation of DNA, restriction enzymes
Enzymes fortreatment of DNA
PCR - general method and applications
PCR DNA: synthesis and size determination - application examples
DNA: sequencing
Introduction of DNA in living cells (transformation)
Cloning and identificationof genes
Gene expression
Silencing of genes
Protein design
Gen banks and gene mapping
Genomes of prokaryotes
Genomes of eukaryotes
Human genome
Functional analysis of the human genome
DNA analytics
DNA arrays
Reporter groups
Gene therapy
High-throughput genome sequencing
Comparative genomics
Pharmacogenomics
Metagenomics
Metabolomics and metabonomics
Glycobiology
Structural biology
Biorefineries
RNA technology
Stem cell technology
Tissue Engineering
ALCOHOLS, ACIDS AND AMINO ACIDS
Ethanol
1-Butanol, acetone
Acetic acid
Citric acid
Lactic acid and gluconic acid
Amino acids
L-Glutamic acid
D,L-Methionine, L-lysine, L-threonine
L-Phenylalanine and L-aspartic acid, Apartame?
Amino acids by enzymatic transformation
ANTIBIOTICS
Antibiotics: abundance, applications and mechanisms of action
Antibiotics: production and resistance
Lactam antibiotics: structure, biosynthesis and mechanism of action
Lactam antibiotics: production
Amino acid and peptide antibiotics
Glycopeptide, polyether and nucleoside antibiotics
Amino glycoside antibiotics
Chinones, chinolones and aromatic antibiotics
Polyketide antibiotics
New strategies for antibiotics
SPECIALTIES
Vitamins
Nukleosides and nucleotides
Biotensides and biocosmetics
Polysaccharides (dextran, xanthan)
Biomaterials
Biotransformation
Steroid-biotransformations
ENZYMES
Enzymes
Enzyme catalysis
Enzymes for analytics
Enzyme analytics
Enzymes in technical applications
Detergent enzymes
Enzymes für starch degradation
Enzymatic starch hydrolysis
Enzymes and sweetenting
Cellulasens and hemicellulases
Enzymes for pulp and paper production
Pectinases
Enzymes for milk treatment
Enzymes for treatment of bakery goods and meet
Enzymes for leather treatment
New startegies for technical enzymes
BIOTECHNOLOGY OF FOOD
Alkoholic beverages
Beer
Fermentierted food
Food and lactic acid fermentation
BAKERS' YEAST AND FODDER YEASTS
Bakers' yeast and fodder yeasts
Proteins and oil from singel cell organisms
BIOTECHNOLOGY AND ENVIRONMENTAL PROTECTION
Aerobic wastewater treatment
Anaerobic wastewater and slugde treatment
Biological off-gas purification
Biological soil remediation
Microbial ore leaching and biocorrosion
THERAPEUTIC AND DIAGNOSTIC BIOTECHNOLOGY
Insulin
Somatotropin and ohter hormones
Hemoglobin, serum albumin, lactoferrin
Clotting factors
Anticoagulants and thrombolytics
Enzyme inhibitors
The immune system
Stem cells
Interferons
Interleukins
Erythropoietin and growth factors
TNF and other pharma proteins
Vaccines, recombinant vaccines
Antibodies
monoclonal antibodies
recombinant antibodies
Immune analytics
Biosensors
AGRICULTURAL BIOTECHNOLOGY
Animal breeding
Embryo transfer, cloned animals
Gen mapping
Transgenic animals
Gene farming
Plant breeding
Plant cell cultures: surface cultures
Plant cell cultures: suspension cultures
Transgenic plants: methods
Transgenic plants: resistance
Transgenic plants as bioreactors
CURRENT TRENDS
Compund screening
Proteomics
Bioinformatics
Metabolism
Metabolic engineering
SAFETY, ETHICS, ECONOMY
Safety in gene technology
Approval of bio- and gene technicologiocal products
Ethics and acceptance
Patents and biotechnology
International comparison

Rezensionen

"...you should have it close at hand on your desktop as you read new articles. I would recommend this reference book...not only to clinical chemists, pathalogists, and medical technologists, but to anyone in medicine who wants to know how all the new therapeutic agents are made and appriciates the impact of biotechnology an medicine and society."
Clinical Chemistry

"...this book is a useful, interesting and colourful guide to modern biotechnology and genetic engineering. It will achieve its objective of providing students with an overview of the field presented in manageable portions and a clear and accessible manner, but it will also be a source of information, a useful reference and an interesting read for any researcher who is working across the traditional boundaries of chemistry, biology or biochemistry."
ChemBioChem

"This pocket guide can be recommended unreservedly for all students and researchers in natural and engineering sciences and medicine, but is also useful to readers with a general interest in biotechnology and genetic engineering. I can certainly agree with the final sentence of the book cover: A perfect introduction to the field - for professionals and students."
Angewandte Chemie IE

Erwähnung in: Process
"...provides a broad coverage of the relevant facts on products, methods and applications in biotechnology and genetic engineering...Instructive yet attractive color illustrations and a didactic approach throughout the book..."
Process worldwide

"Beginners and experts will like this wonderfully composed book."
Journal of Statistical Computation & Simulation

"In the wilderness of biotechnology, Schmid's "Pocket Guide to Biotechnology and Genetic Engineering" is a welcome addition that with all likelihood will find many friends. During the review process it has definitely found one! The book is excellently produced. The figures are as sharp as tacks and as informative as the text...The overall verdict is: useful and recommendable to students and biotechnologists alike."
Engineering in Life Sciences