Cancer Epigenetics (eBook, ePUB)

Biomolecular Therapeutics in Human Cancer
Redaktion: Giordano, Antonio; Macaluso, Marcella

• Format: ePub

Produktbeschreibung

Cancer Epigenetics: Biomolecular Therapeutics in Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and aims to facilitate collaboration between the basic, translational, and clinical sciences.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 420
• Erscheinungstermin: 7. Oktober 2011
• Englisch
• ISBN-13: 9781118005736
• Artikelnr.: 37348261

Autorenporträt

Antonio Giordano, M.D., Ph. D., is professor of biology and medical research at Temple University College of Science and Technology in Philadelphia, Pennsylvania. In 1993 he co-founded the Sbarro Institute for Cancer Research and Molecular Medicine. He has been honored as Knight by the president of Italy and is recipient of the National Italian-American Political Action Committee (NIA-PAC) National Lifetime Achievement Award in Medical Research. Marcella Macaluso, Ph.D., is associate professor of biology and a researcher in the Hormone-Signaling and Cancer Program of the Sbarro Institute for Cancer Research at Temple University in Philadelphia.

Inhaltsangabe

Contributors. Preface. SECTION I: EPIGENETICS AND CELL CYCLE. 1 Epigenetic Modulation of Cell Cycle: An Overview (Micaela Montanari
Antonio Giordano
Marcella Cintorino
and Marcella Macaluso). SECTION II: EPIGENETICS AND CELL DEVELOPMENT
SENESCENCE AND DIFFERENTIATION. 2 Epigenetics in Skeletal Muscle Development (Cristina Giacinti and Antonio Giordano). 3 Epigenetic Control in Cellular Senescence (Heike Helmbold
Wolfgang Deppert
and Wolfgang Bohn). 4 Epigenetic Modulation in Cell Development and Differentiation (Mario Mancino
Claudia Esposito
Raffaella Pasquale
Immacolata Vocca
and Francesca Pentimalli). SECTION III: EPIGENETICS AND GENE TRANSCRIPTION. 5 Epigenetic Control of Gene Transcription (Christian Bronner
Mayada Achour
Thierry Chataigneau
and Valerie B. Schini-Kerth). 6 Epigenetics
MicroRNAs
and Cancer: An Update (Giuseppe Russo
Andrew Puca
Francesco Masulli
Stefano Rovetta
Letizia Cito
Debora Muresu
Flavio Rizzolio
and Antonio Giordano). SECTION IV: EPIGENETICS AND CANCER. 7 The Role of Epigenetic Modifications in Cancer (Michael J. Powell
Vladimir M. Popov
Xiang Wang
Steven B. McMahon
Alexander Mazo
and Richard G. Pestell). 8 MBD4/MED1 Protein in DNA Repair and Demethylation
Cancer
and Other Diseases (Serena Buontempo
Mara Sannai
and Alfonso Bellacosa). 9 Epigenetics in Pediatric Cancers (Roberta Ciarapica
Lavinia Raimondi
Federica Verginelli
and Rossella Rota). 10 Epigenetic Mechanisms in Cancer Formation and Progression (Elisabetta Fratta
Luca Sigalotti
Alessia Covre
Giulia Parisi
Riccardo Danielli
Hugues Jean Marie Nicolay
Sandra Coral
and Michele Maio). SECTION V: EPIGENETICS AND ANTICANCER DRUG DEVELOPMENT AND THERAPY. 11 Recent Advances in the Field of Stem Cell Research: Toward the Definition of the Epigenetic and Genetic Codes of Pluripotency (Gaetano Romano). 12 Potential of Heat Shock Protein Targeting for Human Therapy (Laszlo Otvos
Jr). 13 Advances in Stem Cell Therapy for Cancer Research (Andrew Puca and Antonio Giordano). 14 Epigenetic Targets and Drug Development (Paraskevi Vogiatzi
Maria Irene Scarano
and Pier Paolo Claudio). Index.